Ah that’s the rub! (Shakespeare):
When you reach the end of the tangled rope being weaved that seeks to deceive their are three key players that really matter with what’s being cited above and that is advanced glycation end products they are:
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methylglyoxal
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3-deoxyglucosone
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fructosamine 3-kinase (FN3K)
Sub-factors:
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Glutathione depletion
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Organic sulfur depletion