Bio-decryption Challenge

(Bunny) #1

AMYLASE\LECTIN\GUT FLORA

Something that has been on my mind for a long-time!

For you brainy ones (this is going to be interesting!):

To inhibit (lectin) or not to inhibit Amylase, that is a tricky question?

Bio-decryption Challenge:

Explain what is going on here?

What is causing the real problem?

What are the possibilities with Keto?

Any Long-term efficacy problems?

Any advantages or disadvantages?

Cypher\Cipher:
Raw (vitamins, trace minerals & elements, lectin) vs. Cooked (vitamins? no lectin, trace minerals & elements) Veggies —->Lectins—>Digestion—->Carbohydrate Breakdown—>Epithelial Gut Damage—>Gut Flora (probiotic ecology)—>Amylase—>Amylase inhibitors —>Carbohydrates—->Glucose—->Insulin —->Ketosis —->Weight Loss

Research Resources:

  1. All About LECTINS in Food (The Good, Bad, and Not Too Troubling) https://www.thehealthyhomeeconomist.com/lectins/

  2. Isolation, Identification and Characterization of a New Type of Lectin with α-Amylase Inhibitory Activity in Chickpea (Cicer arietinum L.) http://www.eurekaselect.com/node/154116/article/isolation-identification-and-characterization-of-a-new-type-of-lectin-with-amylase-inhibitory-activity-in-chickpea-cicer-arietinum-l

  3. Characterization of alpha-Amylase-Inhibitor, a Lectin-Like Protein in the Seeds of Phaseolus vulgaris. https://www.ncbi.nlm.nih.gov/m/pubmed/16667338/

  4. Occurrence and purification of .alpha.-amylase isoinhibitors in bean (Phaseolus vulgaris L.) varieties http://pubs.acs.org/doi/abs/10.1021/jf00012a006?journalCode=jafcau

  5. Activation of bean (Phaseolus vulgaris) alpha-amylase inhibitor requires proteolytic processing of the proprotein. https://www.ncbi.nlm.nih.gov/m/pubmed/8310064/

  6. A proprietary alpha-amylase inhibitor from white bean (Phaseolus vulgaris): A review of clinical studies on weight loss and glycemic control https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3071778/

  7. Summary of White Kidney Bean Extract Primary Information, Benefits, Effects, and Important Facts https://examine.com/supplements/white-kidney-bean-extract/

  8. Section 11.4 Lectins Are Specific Carbohydrate-Binding Proteins https://www.ncbi.nlm.nih.gov/books/NBK22545/

  9. Plant Lectins: Versatile Proteins with Important Perspectives in Biotechnology
    https://selfhacked.s3.amazonaws.com/wp-content/uploads/2017/12/bger15-7.pdf

  10. Latent associations of low serum amylase with decreased plasma insulin levels and insulin resistance in asymptomatic middle-aged adults https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3439247/

  11. Recognition and binding of the PF2 lectin to α-amylase from Zabrotes subfasciatus (Coleoptera:Bruchidae) larval midgut. https://www.ncbi.nlm.nih.gov/m/pubmed/25528751/

  12. A lectin gene encodes the alpha-amylase inhibitor of the common bean. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC298176/

  13. Effect of purified lectins on pancreatic alpha-amylase activities http://pubs.acs.org/doi/abs/10.1021/
    jf00016a023?journalCode=jafcau

  14. Effect of Lectins on Salivary and Pancreatic Amylase Activities and tlhe Rate of Starch Digestion http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2621.1987.tb14273.x/abstract

  15. Lectin-tannin interactions and their influence on pancreatic amylase activity and starch digestibility https://www.google.com/amp/s/www.researchgate.net/publication/231543440_Lectin-tannin_interactions_and_their_influence_on_pancreatic_amylase_activity_and_starch_digestibility/amp

  16. Lectin Lock Natural Defense Against a Hidden Cause of Digestive Concerns and Weight Gain http://intelegen.com/nutrients/natural_defense_against_lectins.htm

  17. Improvement Strategies of Leguminosae Biotechnology https://books.google.com/books?id=QCQM7ZmZ5z0C&pg=PA249&lpg=PA249&dq=amylase+and+lectin&source=bl&ots=CU0H8Poqze&sig=rD_cVc8Q5qXgqllRTOQPWwCPKm8&hl=en&sa=X&ved=2ahUKEwiqsC_4dLYAhVQwWMKHQ1JCHEQ6AEwB3oECAoQAQ#v=onepage&q=amylase%20and%20lectin&f=false

  18. Colon polyps

  19. https://www.ketogenicforums.com/t/diverticulitis-crt/27664/9?u=atomicspacebunny

  20. Period after starting keto?

  21. Insulin and Glucogon

  22. Dirty Genes Summit & Keto by Dr. Ben Lynch

Colon polyps
(Consensus is Politics) #2

After some deepthought, I say…
42

(Bunny) #3

imageimage

(Consensus is Politics) #4

Indeed. 42 is the answer to life, the universe and everything.

(Consensus is Politics) #5

It only appears that I am avoiding the question here. Thats because the Lectin cake, is a lie.

(Bunny) #6

That’s what is so puzzling?

Lectin?

Looks keto?

(Consensus is Politics) #7

At first glance they look Keto. Almost like fiber. Maybe a type of fiber based on descriptions.

They seem to be both beneficial and poisonous at the same time. The can pass though the digestive tract without being broken down, (fiber like?) and they can cause allergic like reactions as well. Creating antibodies against the lectins (I’m not sure yet if that’s a good or bad thing. I’m open to opinions either way, convince me).

Some foods containing pectin are poisonous when raw. Red kidney beans, raw contain about 50,000 units of lectins (units undefined) +/- about 20,000 units. A handfull of raw kidney beans will cause lectins poisoning (a protein toxicity that prevents exocytosis and repair of damage cells). Fully cooked (undefined term) red kidney beans have only 200-400 lectin units.
[im not sure I’ll ever trust a kidney bean again😱]

I don’t think I’m willing to try and find out.

(Consensus is Politics) #8

Castor beans are also a really good source of lectins. I don’t think cooking them will make them edible though. There’s that whole ricin thing.

“While some lectins are beneficial, other lectins like ricin will kill instantly with just one molecule. So lectins fall along a spectrum of beneficial to deadly, with many being toxic and inflammatory to various degrees.“

:face_with_monocle:

(Bunny) #9

What really blew me away in Dr. Guntry’s Video was how the crickets were dead from the inability to digest (amylase inhibition) the tomatoes (high in lectin; carb blocker).

The other mind blower was how just cutting out the foods on Guntry’s list (does not work on everyone) of what not to eat lost all the weight they wanted too!

The last one was how lectin damages the stomach lining and gut flora ecology!

Variety of vegetables (high in lectin) and type of vegetables (including grains, dairy and some meats consumed) is seemingly a factor?

(Consensus is Politics) #10

One of the things I read about lectin in plants is it insecticide properties. That might be one of the genes scientists are playing with for crops to become more insect resistant. Wow. Imagine if they screw that up and get corn or wheat to create ricin? :speak_no_evil::poop:

(Bunny) #11

What I am gathering from this info?

It also seems as if Lectin is blocking the amylase enzyme from digesting carbs, then the body (stomach, intestines) is seeing it as a foreign substance which basically sits in the gut and rots (bad bacteria—-> polyps & diverticulitis); hence gas and bloating, but also turns the majority of what is not being digested by the amylase enzyme into fat and storing it as fat?

In other words it is not becoming a probiotic and also destroying the pre-existing probiotic ecology of the gut flora! This could also throw the Lipase, Bromelain, Trypsin, & Nucleases enzymes out of whack also (symbiotic symbiosis)?

Should the FDA and Congress be compelled to to list LECTIN content or issue WARNINGS in livestock, sea food and agriculture industries?

Somebody please tell me I’m wrong?

Lectins - The Plant Paradox