IIRC, and I may not, last time I heard her/JF talk about this was in relation to 24-36 hr fasts, when after 24 hours your body starts breaking down the old proteins and disposing of them. Skin comes under this category.
Actually, I think JF mentions it here. (The audio isn’t great, and the hosts have some weird setup that REALLY aggressively ducks the audio of the guest when ever they make any kind of noise, so bits get missed, but it’s well worth a watch for a lot of people, I think.)