Karim's Extended Fast Tracker - come along for the ride


(PJ) #462

Yeah, makes sense.

I wonder if there is a certain number beyond which fat is not easily able to be released, do you know?

I only started measuring my glucose again yesterday (I used to do it many years ago. I’m totally type-A about measuring and tracking everything). It’s been 74 both days but then again, I’m fasting!


(Karim Wassef) #463

Fat can continue to be consumed up to very high levels. There’s actually multiple ways it can be catabolized.

Fat can be broken into glycerol and fatty acids. The glycerol can be made into glucose or directly into energy. The fatty acids can also be used directly by a lot of tissue. This is carried around the blood in cholestrol and it’s why cholestrol goes up when you fast, but it’s not unhealthy.

Once the body has “saturated” its use of fatty acids, the liver starts converting the excess into ketones and this can continue to climb… I got to a ketone level above 9 on my phase 1 fast around day 18.

Only some parts of the brain, nerves and red blood cells need glucose. That’s because they don’t have mitochondria so they can’t use fatty acids or ketones. They’re obligate glucose users. That’s why the body needs to make glucose and it trains every other cell to use ketones instead to spare it for those cells.

It can make glucose from protein (lean mass), glycerol (fat), lactate (comes from glycogen oxidation after being used in muscle), and propionyl CoA (fat and muscle)… this is gluconeogenesis and it’s the one thing that concerns me during fasting or protein restriction and what I’m trying to learn the most about now.

For someone who is a carb burner, this is extreme and causes massive lean mass loss and wasting… that’s why calorie restriction is so destructive. What I can’t figure out is the consumption of lean mass by fat adapted bodies while fasting.


(Karim Wassef) #464

Ending day 3 with 49G, 4.1K = 0.66 GKI

That was faster than I thought… but tomorrow morning I’ll likely be back up to ~2

Interesting that I’m already in autophagy but my weight has barely worked through my water and food flux… I’m assuming it’s because my historic fasts have made me fat and “fast adapted”.

Little cold but no chills yet so that’s contradicting my concept that the chills are connected to being in autophagy…

So I’m going to propose a new theory that the chills is a function of the reduced state of gluconeogenesis (lean mass catabolism leveling to a low level)… Why? Because amino acid catabolism is inefficient and generates heat… once the body gets to the other side of that stage, it starts to conserve energy and that includes heat… just a theory

Also, the low glucose level (under 50) says that the process of gluconeogenesis is also starting to slow down. If that’s true, then I should start feeling the chills tomorrow.

Muscles definitely flat even though I’m feeling strong and my lifts today were solid.

Very clear minded and calm.


(PJ) #465

My temperature has gone up .1 degree each f six days. (I run a full point below normal.) I’m nearly to normal! Not sure why!


(Karim Wassef) #466

Are you fasting ?
Keto could naturally have more protein than your diet previously and that may be generating more heat.


(PJ) #467

I am normally keto, though I was only mod carb the prior month. But I’m on day 9 of a base-nutrient fast. (Water and supplements.)


(Karim Wassef) #468

So you’re experiencing temperature increase after 9 days of fasting? That is unusual.

Where are your glucose and ketone levels at?


(Karim Wassef) #469

Day 4

So down another 2.4lbs so down 9.4lbs total from day 1 to day 4… still losing water, but I think the food flux is done.

With 60G, 3.7K = 0.9GKI… my expectation that I was going to bounce back up to ~2GKI was off. So I expect that days 4 and 5 will remain in autophagy unless I artificially deflate ketones by lifting and adding physical stress. The metric would go up but it wouldn’t change my true state of remaining in autophagy so I expect that some lean mass loss is to be expected. I’m hoping it’s digestive organ shrinkage, etc… since that should recover well based on the long fast and refeed.

I feel fine. Good clarity and calmness.

Less energy than usual this morning but I was in a rush and didn’t get my cold shower timed in… so had to just go with a normal shower.

Cold but still no chills…


(Karim Wassef) #470

(Karim Wassef) #471

I’ve been thinking of my physical stressors and why they consume ketones… sauna, cold showers, ice baths, cold packs, UV…

I think it’s adrenaline. All these activities stimulate substantially more blood flow and that up regulates the adrenaline. Adrenaline is one of the hormonal keys to releasing lipids from adipose tissue too so it may actually be creating a push pull effect. It drives more circulation consuming energy and allows for more fatty acid release too.


(Karim Wassef) #472

Pre-sauna: 58G, 3.8K = 0.85GKI

Post-sauna: 61G, 3.0K = 1.13GKI

went for 35 minutes today which is my personal best. Interesting that the glucose spiking response I used to have is almost completely gone. I had expected that the refeed cycle may have brought it back but it looks to be gone.

I also found a place that does both DEXA +
RMR for $85 total. The last place was $75 each = $150… so I might rebudget and schedule 3 (or 4) instead of two. I had planned to stop testing after the one week non-fasted carnivore phase 3 but I might rethink it to see the long term effect of phases 1 and 2


(Karim Wassef) #473

Ok … booked for April 15th. Tax day.

That Monday will be immediately following two 5 fast : 2 feed cycles so halfway through phase 2.


(Karim Wassef) #474

Afternoon 51G, 4.8K = 0.59GKI.

Dry fasting tomorrow until 1pm as is my Friday usual… not looking forward to it but I just feel that it’s a necessary “finale” to the 5 day fast before breaking the fast in the evening.


(Karim Wassef) #475

So I have to ask you guys… is my thread a little “dry”?

Not many responses to my thought exercises or feedback to my updates… :slight_smile:


(Windmill Tilter) #476

I don’t think it’s dry. I find interesting tidbits on here every day. :+1:


(Karim Wassef) #477

Ending the night at 45G, 6.0K = 0.42GKI for day 4…

On my last fast, it took 6 days to get to 6.0 ketones. This time, it took only 4 days… I wanted to say that I was starting from a higher staring ketone level but that’s actually not true.

On my long fast, I started with a pre-fast ketone level of 0.7 and there was little fiber in my gut… ribeyes mostly.

On this short fast, I started with a pre-fast ketone level of 0.5 and with plenty of fiber that I expected to continue to generate energy for a couple of days.

Not sure why I’m experiencing a faster ketone ramp but it may just be a faster adaptation in response to my long fast… residual effects.

My goal was to stay in the 1-3 window and I just couldn’t keep it there (failure!). I overshot for the first couple of days and then plummeted to sub 1 in the last couple.

I’m going to follow through as an experiment but I am still concerned about lean mass loss with GKI < 1 … but… for science… I will persevere

If nothing else, it might continue to reduce my visceral fat.

I will say that I haven’t experienced chills this time.

The prospect of eating tomorrow is not necessarily pleasant. I was irritable today and when I considered this, I realized that the prospect of eating made me anxious. I tried to imagine that I was going to skip this refeed and just go for another week and I immediately calmed down. All anxiety disappeared and I was at peace again… I kid you not, it’s all mental.


(PJ) #478

Yeah, I find that so far when fasting, everything is mental. Which to me just makes it that much more important that one consciously take control of “designing their mind” for the occasion.


(Neil) #479

Not all! I’m following along with interest. I just haven’t really had anything useful to add. :slight_smile:


(Omar) #480

It is not dry, but it is fat :joy:

with wealth of data, people who lack the ability to link the different observation may like to see executive :grin: report.

but it is inspiring thread for sure. and you have lots of persistent power.


(Karim Wassef) #481

Thanks guys.

I will say that I’m trying something new for loose skin and it seems to be very effective while fasting. Nothing else has worked this well but I’m not ready to share yet until I have tested it long enough to ascertain that it doesn’t have negative side effects. I am taking pictures so you’ll be able to see the before and after.

I also upped my daily dose of Leucine to 4g post workout. I think that this may be part of the reason I saw a much more dramatic ramp in ketones. If someone wants to intentionally get into autophagy fast, this seems to be it.

In fact, I suspect it’s also why I couldn’t get out of autophagy for days while eating … and sometimes even overeating carbs (70g). I never got out of ketosis. I would really like to study the effect of Leucine on RMR, especially while fasting.