That’s unfortunate – as a general rule the side-effects of Berberine as much few and the gut issues, if present, are much milder than metformin.
What do you take in place of Berberine or were you just testing it?
My wife couldn’t take metformin due to terrible gut issues (several forms) and then Januvia was (almost) life-threatening for her due to low blood sugar excursions even though it didn’t hold her high readings down either.
So Januvia was basically worthless and then dangerous to her – eventually at least twice a week she was incapacitated, sometimes while driving or otherwise outside the home…
She started with a very simple paleo diet and dropped Januvia at her (2nd) doctor’s direction and was off it within a couple of days – with complete blood sugar control.
Never again did she have a low excursion and the number of high readings (above 140-ish) can be counted on one hand since last summer.
She recently adopted keto about a month ago and did her first extended fast last week.
We started Berberine during this time also, but only moved to 3 x 500 mg over the last couple of days – but it seems to be going fine and there is some indication that it’s holding down our blood glucose (but maybe we don’t need it so it’s too early to tell.)
All sorts of good additional benefits to Berberine and much fewer side-effects or reduced levels make it a great alternative for all but the apparently rare people who can’t tolerated it.
I’ve read that reducing the dose to 250mg or giving a few weeks (if it can be tolerated at all) commonly resolves most of the uncommon gut issues but I don’t know anything about “back numbness” as a reported side-effect.
Please report anything else you know or learn about Berberine…