Dr. Gorski, the author of the article/editorial (and editor of the web site), is an advocate for scepticism of treatments that appear to be quackery. He does not dismiss the ketogenic diet as a cancer treatment tool. But he does apply some suitably harsh critique. It is an important health topic, life and death for some people, so it deserves a thorough investigation. He seems well credentialed. But that does not immunise him against bias.
Then he uses the âargument from ignoranceâ fallacy in informal logic by asserting that the proposition being presented by Dr. Seyfried, of cancer being a metabolic disease, does not have enough evidence from double blinded clinical trials. This is despite scientific literature quoted by Dr. Seyfried that shows promising observations in animal studies (acknowledged by the author), and strong indications of positive outcomes from human case reports. Dr. Gorski may be right that the ketogenic diet may not be as effective as hoped in treating cancer, but the absence of evidence, also allows the possibility that Dr. Seyfried and co-workers may also be right about the effectiveness of the ketogenic diet in a cancer treatment protocol. So this paragraph is no help at all. Itâs mainly an observation on the contemplation that an absence of evidence can be one of hope.
This article is from 2014. From listening to the recent 2 Keto Dudes podcast with Dr. Seyfried it sounds like there is more up to date information to explore. So it is good to ask to examine the veracity of any recent studies.
From my limited knowledge on the benefits of the ketogenic diet in the treatment of cancer, the initial simple answer of cutting off a cancerâs glucose fuel supply and starving it, seems to have cases in which it works quite well (the brain tumours mentioned in the article), and rare cases in which ketones may be the preferred fuel for some cancer cells. Sorry I donât have a reference to hand. There may be more on Google Scholar. Dr Seyfriedâs work shows up on a search.
I think it is important that an oncologist and cancer patient consider, at least be aware of and up to date with, the Warbourg effect and the use of ketogenic diets for the treatment of some cancers. But also be aware of the cancer types where the ketogenic diet may not be helpful.
It seems Dr. Gorski and I might agree. Cherry picked from the article (it was a good read):