Sugar causes cancer


#1

(VLC.MD) #2

Slightly clickbait title :slight_smile:

“… although this in no way means that sugar causes cancer.” (which kinda is your title !)

“Whether increased sugar intake enhances cancer growth, or whether cancer’s sugar breakdown system could be interrupted, are still questions that remain unanswered.”

Cool study though. Thanks for sharing.

Original article is quite a challenging read.

https://www.nature.com/articles/s41467-017-01019-z

Title: Fructose-1,6-bisphosphate couples glycolytic flux to activation of Ras

Conclusion: We have identified a direct regulatory connection between Fru1,6bisP in glycolysis and the Ras proteins, that seems to be evolutionary conserved in yeast and mammalian cells. It is responsible for induction of apoptosis in yeast cells with overactive influx of glucose into glycolysis and stalled flux at the level of GAPDH. We suggest that Fru1,6bisP activation of Ras constitutes a key mechanism through which the Warburg effect might stimulate oncogenic potency.


#3

Purposely so…


(VLC.MD) #4

Worked. Genius.

Fructose-1,6-bisphosphate in a title is pretty much a topic killer. Fact.


(Bacon for the Win) #5

I read the original. An hour of my life I’ll never get back. Trying to show SIL that even though Dad is in final stages, sugar is still not a good idea. I won’t share this article with her, too techy.