Spermadine for autophagy/calorie restriction mimicking?

#1

Someone on Mark’s Daily Apple posted this link noting it can “turn on autophagy without fasting.” What do you all think of this? Read here.

#3

Thank you for the response. I guess the jury may be out for a while, but will be interesting to follow this.

#4

At first, due to the name of the stuff, I thought this was some kind of parody thread. :slight_smile: But according to Wikipedia, it’s real, and it was “originally isolated from semen.”

Whaaaa??? Ye gods!

I was totally laughing my ass off reading that Wiki entry! It mentioned the autophagy as a major affect. It also mentioned it being good for hair growth! Just imagine! Bwahahahahaha!!!
Does this mean you hear the “boom chicka wow wow” music every time you wash your hair now???

OMG! I can’t stop laughing!!! Mods and Admins, please don’t ban me for this post - just disappear the post if you need to. I’ll be over here in my little corner just howling with laughter and promise to be good and not post any much more in this thread!

#5

Oh wow, I had no idea. That is too funny!

(Bunny) #6

WOMAN DEVELOPS IQ OF 220 AFTER DRINKING SPERM EVERYDAY FOR A YEAR - World News Daily Report

A student from UCLA has just achieved the highest score in history on an IQ test designed by Mensa, and she claims her astonishing result is due to her daily ingestion of sperm.

26-year old Alicia Franklin, was already a member of the high IQ society Mensa, after scoring 154 in her qualification test in September 2015.

The young woman searched for ways to improve her intelligence, and after taking a new test three weeks ago, it seems that she succeeded.

She allegedly raised her IQ by more than 65 points in 13 months, after she began ingesting a daily dose of fresh sperm. Her new results show that her cognitive intelligence, her perception and her memory have all greatly improved.

According to her latest supervised test, her IQ is now evaluated at 220, making her smarter than Stephen Hawkins, Albert Einstein and Leonardo Da Vinci, and placing her among the most intelligent people in human history.

“I did a lot of research on ways to improve my intelligence, and I found out that drinking sperm was probably the simplest and most efficient of them all,” she told Science Today. “There are many nutrients and chemical elements in it that are extremely important for the development of the brain.”

According to experts, Ms. Franklin’s theory is, indeed, founded on scientific facts, and it is very plausible to believe that people ingesting sperm could develop better intellectual capacities.

Semen contains over 200 proteins and several helpful vitamins and minerals, including vitamin C, calcium, chlorine, citric acid, fructose, lactic acid, magnesium, nitrogen, phosphorus, potassium, sodium, vitamin B12 and zinc.

It also contains mood-enhancing compounds such as cortisol, estrone, oxytocin, thyrotropin-releasing hormone, prolactin, melatonin and serotonin.

Many of these elements could help get a better sleep, feel less stress and be in a better mood, which are all factors which may help to perform better. …More

Research:

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Spermidine (polyamine)

  1. Spermidine promotes mating and fertilization efficiency in model organisms

  2. The Chemical Spermidine In Semen Can Make You Live Longer

  3. Sperm(idine) answers the next generation

  4. Spermine and spermidine - Royal Society of Chemistry Kiki Sanford explores how polyamines found in semen could be related to a long and healthy life…

  5. Polyamines Help Control Embryonic Stem Cell Differentiation

  6. Natural Ingredient for Healthy Hair and Nail Treatment with Anti-ageing

  7. An essential role for polyamine biosynthesis during human granulopoietic differentiation

  8. Mechanistic Studies On the Role of Polyamines and Microvesicles in Tumor Growth and Hypoxia- mediated Angiogenesis

  9. Relationship between food polyamines and gross domestic product in association with longevity in Asian countries

  10. Polyamines of Plant Origin – An Important Dietary Consideration for Human Health

  11. Polyamines in aging and disease

  12. Polyamines: Bio-Molecules with Diverse Functions in Plant and Human Health and Disease

  13. Increased Polyamine Intake Inhibits Age-Associated Alteration in Global DNA Methylation and 1,2-Dimethylhydrazine-Induced Tumorigenesis

  14. Induction of autophagy by spermidine promotes longevity

#7

Just for clarification for anyone thinking Bunny’s cited article about the high IQ girl is legit, the source, World News Daily Report, is a “fake news, satirical” site. It’s all made up. Think “The Onion”. I haven’t checked her other references.

Bunny is a thorough and fantastic researcher, so there may be some real truth nuggets in some of this. I dunno, and I’m too busy laughing over here to look into any of it. I just felt someone needed to stop for a second and say, “yeah, we’re having some fun over here, don’t take us too seriously.”

@atomicspacebunny, you are hilarious!

OK, back to the thread… :joy: :rofl: :laughing:

(Bunny) #8

Tank you, tank you!

…Bows!

(Bunny) #9

…Considering that the pancreas contains the highest concentration of spermidine (Nishimura et al., 2006), it might be expected that spermidine, or polyamines in general, play an important role in maintaining the function of the pancreas. …More

(KCKO, KCFO 🥥) #10

Thanks Ladies, I needed a good laugh today.