This was posted over on the keto subreddit, I’m about half way through it but thought @Richard and @carl (and others) would be interested
Randomized controlled trial of keto vs. "my plate" for t2 diabetes
CHawkins
(Carol Hawkins)
#2
Well so far this looks great:
More than half of the participants in the intervention group (6/11, 55%) lowered their HbA1c to less than 6.5% versus 0% (0/8) in the control group (P=.02)
richard
(Richard Morris)
#3
I’ve not heard of the journal of medical internet research before. It is an open access journal run by one guy, but it’s got a higher citations rating than PLOS One.
The study is a small pilot, but the results are fascinating. Surely some Diabetes Association somewhere will fund a well powered study to test this. If for no other reason as a liability shield against blow back from SOMEONE ELSE doing it and giving type 2 diabetics a legal basis to litigate in a class action for being put on the “My Plate” diet shown to be ineffective at glycemic control, weight loss, compliance, and lipid regulation.
| Intervention | Control | |
| HbA1c | -0.8% | -0.3% |
| reversed T2DM to pre-diabetes | 55% | 0% |
| weight loss | -12.7 kg | -3.0 kg |
| 5% weight loss | 90% | 29% |
| Triglycerides | -60.1 mg/dl | -6.2 mg/dl |
Look at that triglyceride drop, that’s the money shot right there.
I’m pretty sure if a Diabetic organization put me on the control (standard of care) after I saw this result that would open them up to litigation. Given that that 0.5 % point difference in HbA1c is a roughly 11% GREATER risk of diabetic complications. They would have to have a pretty bloody good explanation why they were increasing my risk of diabetic complications by 11%.
jmbundy
(John)
#4
Dropout rate is higher than I would like with such a small sample, but I find it very surprising that only 1 person (8%) of the intervention grouped dropped out while 46% of the control group dropped out. That means that despite all the whining about how hard it is and how people can’t possibly give up their pasta and bread, it was apparently much easier than sticking to a low-fat low-flavor diet.
Seriously, if half the people can’t make it 32 weeks with what the government recommends you have a severe problem. All the nay-sayers complain that keto is not sustainable, I think this is proof that SAD is even worse.