Nicotine on Keto

Aj6155 · 2018-02-17 13:09:40 UTC

Hello all. Yesterday was week 3 on keto. My Blood Ketones have been stable between 2.5 and 3.5 for the past 10 days or so. I was wondering if anyone had any good links For research done on the effects of nicotine on the metabolism specifically, nicotine patches, lozenges and gum causing glycogenesis in the liver and how this may affect Ketosis. Thanks! #KCAKO!

Darlene_Horsley · 2018-02-17 20:05:17 UTC

I don’t have any research articles but it seems that I have read nicotine causes higher insulin levels.

cspell · 2018-02-20 19:55:12 UTC

I recently quit nicotine gum after reading some material online that it can promote insulin resistance. Here is link to one of them from PubMed. I’m hoping I’ll have better fat loss results …

ncbi.nlm.nih.gov

Long-term use of nicotine gum is associated with hyperinsulinemia and insulin resistance.

B Eliasson, MR Taskinen and U Smith, Circulation, Sep 1996 01

Insulin sensitivity and cardiovascular risk profile were examined in 20 healthy, nonobese, middle-aged men who were long-term users of nicotine-containing chewing gum and in 20 matched control subjects who did not use nicotine.Long-term use of nicotine-containing chewing gum was associated with insulin resistance and hyperinsulinemia. The degree of insulin sensitivity correlated negatively to the extent of nicotine use measured as plasma cotinine levels.These findings suggest that nicotine is the major constituent in cigarette smoke that leads to insulin resistance, metabolic abnormalities associated with the insulin resistance syndrome, and increased cardiovascular morbidity. Thus, the use of nicotine replacement therapy during smoking cessation should be transient and limited.

Dipper_Actual · 2018-02-20 20:22:07 UTC

Disclosure: nicotine is my vice.

If you’re getting just nicotine, I don’t know that dropping it improve much. According to Taubes, it’s impact in lipoprotein lipase helps muscle burn fat and adipose tissues take up less. Not sure of the intensity of the effect, or if there’s a difference from getting it through (preferably not smoking) different delivery methods, but this could be the basis for the observation that smokers gain weight after quitting.

Dipper_Actual · 2018-02-20 20:23:54 UTC

So the question is, what tissue would you rather be insulin resistant, relatively speaking? I don’t mind adipose tissue being more IR than muscle, personally.

Julie_Ann_Evans · 2018-09-24 12:30:41 UTC

I know that the nicotine they put in cigarettes raise the insulin in our bodies. If we aren’t taking in sugar, wouldn’t this be a negative affect to what we are aiming for?