Live longer with Keto


#1

Keto lengthens life but it’s difficult to maintain?


(Tim) #2

You know, because if you fail, then you might feel bad about yourself. Can’t have that. Probably best if we never attempt anything. Ever.


#3

The irony in their contention that keto is difficult to maintain is that this is the EASIEST WOE I’ve ever encountered.


(Sheri Knauer) #4

Im having a real difficult time choking down my eggs, bacon, and avocado. Guess I need to swap it for a bowl of heart healthy raisin bran with skim milk, toast with margarine, and a big glass of orange juice.


(You've tried everything else; why not try bacon?) #5

BTW, don’t get too worked up about the study itself. The significance of the correlations is only p < 0.05. In real science, the significance has to be at least p < 0.001 for people to consider the correlation worthwhile.


#6

Yes, I get that. Just stumbled on the article and thought I would throw it up here for discussion.


(You've tried everything else; why not try bacon?) #7

Sorry, Todd, I wasn’t trying to pour cold water on you. It certainly is nice to see that some of this research is making its way into the mainstream culture.

What probably made my post sound critical is my disappointment in the study itself. I have pet rats, which are dear sweet creatures, and they have such short life-spans it just isn’t fair. I am looking for evidence that putting them on a ketogenic diet might prolong their lives. This study is just not what I’m looking for.


(Jessica) #8

I LOVE your plate!!


(Tim) #9

I agree completely, in the physiological sense. The only real difficulty in my experience is a social one (which does not need to be even that hard) but the same can be said of any diet / WOE that bucks conventional wisdom.

And, the more widely it is adopted, the easier it becomes.


(Duane Hewitt) #10

Disagree strongly with this point. p<0.001 is reasonable for a DNA homology search not for a study of this complexity.

In vivo studies are messy.

These studies are each a tour de force with huge implications especially in the context of how it dovetails with the groundwork in caloric restriction, rapamycin and metformin.

Drilling down into the diets used it is interesting that the animals that received more polyunsaturated fats did not display lifespan extension under ketogenic diet versus the study which used mainly lard for low carb/ketogenic did have survival curve shift.

The protein results are interesting.

Journal references.

“Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice.”
Newman, J.C. et al., (2017) Cell Metabolism 26:547-557.

“A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice.”
Roberts, M.N. et al., (2017) Cell Metabolism 26:539-546.