Links to papers, articles and videos

(Michael) #1

Happy to update as suggested, but here are a few links to help people start reading on a few of the topics. This list is certainly neither complete nor exhaustive, but instead a starting point.

Links for Medical Issues

Nutritional Ketosis

Papers

  1. Long-Term effects of ketogenic diet on obese patients https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2716748/
  2. Beta-HydroxyButyrate https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640868/
  3. 2 year long term effects of ketogenic diet https://www.frontiersin.org/articles/10.3389/fendo.2019.00348/full
  4. as above https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6561315/
  5. Effects of carbohydrate restriction on Type 2 diabetics https://journals.physiology.org/doi/abs/10.1152/ajpendo.00165.2020?journalCode=ajpendo&
  6. Nutritional ketosis and mitohormesis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828461/
  7. Nutritional ketosis for weight and metabolic https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6472268/
  8. Induced and controlled ketosis for obesity and metabolic https://pubmed.ncbi.nlm.nih.gov/28433617/
  9. Crohn’s disease treated with ketogenic diet https://www.semanticscholar.org/paper/Crohn's-disease-successfully-treated-with-the-diet-Tóth-Dabóczi/5a95638addfc55df29c8a8156951a95f1c1665f4
  10. Metabolic effects of keto adapted marathon runners https://www.sciencedirect.com/science/article/pii/S0026049515003340
  11. hormonal response to a carb restricted diet https://pubmed.ncbi.nlm.nih.gov/12077732/
  12. Effects of a 12 week ketogenic diet https://pubmed.ncbi.nlm.nih.gov/30803508/
  13. Ketogenic diet and fasting to treat Multiple Sclerosis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941322/
  14. Effects of web-based low carb treatment https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7511867/
  15. 2 year ketogenic diet effects on cardiovascular disease with type 2 diabetes https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7724865/
  16. The carbohydrate insulin model https://academic.oup.com/ajcn/advance-article/doi/10.1093/ajcn/nqab270/6369073
  17. Effect of ketogenic diet on glycemic control https://www.cureus.com/articles/42538-effects-of-the-ketogenic-diet-on-glycemic-control-in-diabetic-patients-meta-analysis-of-clinical-trials
  18. Comparison of diets https://jamanetwork.com/journals/jama/fullarticle/205916

Articles/Videos

  1. Nutritional Ketosis FAQ https://www.virtahealth.com/faq/ketosis-ketogenic-diet-faq
  2. Who benefits from high ketones? https://ketodietapp.com/Blog/lchf/the-ketone-craze-who-really-benefits-from-high-ketone-levels#toc_4
  3. Flawed paradigm derails obesity treatment https://www.statnews.com/2021/09/13/how-a-fatally-tragically-flawed-paradigm-has-derailed-the-science-of-obesity/

Autophagy

Papers

  1. An overview of the mechanism of autophagy https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2832191/
  2. Regulation of autophagy by amino acids and mTOR https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4580722/
  3. Autophagy in neurodegenerative diseases https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739982/
  4. Mitochondrial fission and autophagy in the heart https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032809/#idm140713656833488title
  5. The coming of age of chaperon-mediated autophagy https://www.nature.com/articles/s41580-018-0001-6
  6. Therapeutic modulation of autophagy – which disease comes first? https://www.nature.com/articles/s41418-019-0290-0
  7. Autophagy modulation as a potential therapeutic target of disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518431/
  8. Therapeutic Targeting of Autophagy in disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799234/
  9. Autophagy modulation for Organelle-Targeting therapy https://www.intechopen.com/chapters/51740
  10. Dietary Energy Modulation and Autophagy (re Cancer) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674637/
  11. Autophagy: Cellular and molecular mechanisms https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990190/
  12. Short term fasting produces neuronal autophagy https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3106288/
  13. Nutrient sensors coordinate autophagy https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4267857/
  14. Rapamycin and fasting sustain autophagy https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6155349/
  15. Monitoring autophagy https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835977/
  16. Pancreatic cell autophagy https://www.researchgate.net/publication/44587685_Autophagy_in_health_and_disease_4_The_role_of_pancreatic_-cell_autophagy_in_health_and_diabetes
  17. Rapamycin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972801/

Articles/Videos

  1. How to trigger autophagy https://josephtramazzo.medium.com/autophagy-fasting-part-2-how-to-trigger-maximize-autophagy-78a137b787b7
  2. Autophagy – a cure for present day diseases? https://www.dietdoctor.com/autophagy-cure-many-present-day-diseases
  3. Autophagy and Fasting: How to bio-hack your body https://www.youtube.com/watch?v=96dv7Xrgksw
  4. How to measure autophagy at home https://siimland.com/how-to-measure-autophagy-at-home/
  5. Top autophagy benefits https://www.youtube.com/watch?v=XLj2Qu4SuNQ
  6. The profound benefits of fasting and autophagy https://besynchro.com/blogs/blog/the-profound-benefits-of-fasting-and-autophagy

Fasting

Papers

  1. Molecular Mechanism of Fasting https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946160/
  2. Total Fasting in the treatment of obesity https://pmj.bmj.com/content/postgradmedj/44/507/58.full.pdf
  3. Prolonged fasting-induced metabolic signature in humans https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0200817
  4. Clinical Data for Extended Fasting https://www.sciencedirect.com/sdfe/pdf/download/eid/1-s2.0-S0140673666929254/first-page-pdf
  5. Liver and Kidney metabolism during prolonged fasting https://www.ncbi.nlm.nih.gov/pmc/articles/PMC535723/
  6. Alternate day fasting reduces insulin resistance https://www.healio.com/news/endocrinology/20190801/alternateday-fasting-cuts-insulin-levels-resistance-in-half
  7. Complete starvation for 50 days https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982520/
  8. Therapeutic fast of 382 days https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2495396/pdf/postmedj00315-0056.pdf
  9. Fuel metabolism in starvation https://pubmed.ncbi.nlm.nih.gov/16848698/
  10. Refeeding Syndrome, what it is, how to prevent and treat https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2440847/
  11. Circulating lipids in men on 2-3 day fasts https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7543058/
  12. Effects of rapid weight loss when fasting https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2625789/?page=6
  13. Metabolic effects on human and mice blood in vivo when fasting https://www.tandfonline.com/doi/full/10.1080/15548627.2016.1271513
  14. Protein, fat and carbohydrate requirements during fasting https://watermark.silverchair.com/12.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAr8wggK7BgkqhkiG9w0BBwagggKsMIICqAIBADCCAqEGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMXIgSUgZB-ODltdMEAgEQgIICcqEsyNuHryxqPypz4kuM_BPk56O-I4yCJZsko2U9X7VbqN3x5M2PIUs8J_xCEB4PXZqnykZsTuJCziLHJnG0S6uTKZn8PkjbtyLlk5K4Dss96aRxLkEHpHJDDTG-RuT1OQLHHjFYw67nFIbFuSao3aavAsfLXI8-72q9N7UG-NSdnRkZgRj_rJ-hszDUbrC9noxHlStB0uO7uxUuNjA3x-yc4a_anGwfLH45AZZEb6tyU8VhRqZchCF2EbWm0q2XgdwtUmYxzkMIYVHn55PNa9Hz2MoQnUWC7ON3YgM8-p7c3apd8dKbws6G3guL53zafT0X544L-1cTJii5V0LmAxbg_Y7XgrWRrT6RO11sIJf-HaDPvDO3EgG3UIOi4pFP1PYgSnx89SHq1ulh_NP76h73JRxOBaH4tO0Zy4lnqtDCuraNRNzA35btr15OHfD2ybgA4lKa-U88M75soEtOvoyV9aWYnmojmDwytNvMCrbDkBENf-Ah5OaI2GgFHf8vohmPKLO-wLCQFNfKqRxUOooc4eYjFWrLGc5Ggh9V2LMNxSvv8NoC5KZeuTXOg6U59EgkmDokbzkZ0nJ2_fP7T8fVxRx_lQHAKkTr0KMiuDh2jD0bsWTueMyO5l-79bVK0TawIlJodddPhMucXkrd5vGRiVw2PVhO5esbLzNzxsJkI9VZ__zCpsS7e3Jk794weQys7PD9Bc1d3eM5Je7hgr6BB2TyhlNi-buX8IfG2PDTLGTexfHFFR9rh2jqdorijkLlyan-3Fut4283crAzjbmv6o8i3PfvPW3KdMOBUwWxNQJEySAZYjFPpeKQqLNheg_W
  15. Therapeutic fasting for Type 2 diabetes https://casereports.bmj.com/content/2018/bcr-2017-221854.full
  16. Anabolic effects of leucine and soy protein when fasting https://pubmed.ncbi.nlm.nih.gov/27265181/
  17. Fasting protects non cancer cells from chemotherapy, but not cancer https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2448817/
  18. Fasting Metformin and Cancer https://www.cell.com/cancer-cell/fulltext/S1535-6108(19)30203-X

Fiber (good and bad)

Papers

  1. Fiber and gastrointestinal disorders https://pubmed.ncbi.nlm.nih.gov/23545709/
  2. Fiber implications in disease https://pubmed.ncbi.nlm.nih.gov/3020970/
  3. Reducing fiber reduces constipation https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3435786/
  4. High fiber does not protect from diverticulosis https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724216/
  5. Facts about fiber https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659900/

Articles/Videos

  1. The truth about fiber. https://www.diagnosisdiet.com/full-article/fiber
  2. Is fiber bad for you? https://bengreenfieldfitness.com/article/nutrition-articles/is-fiber-bad-for-you/

Thiamine and Diabetes

Papers

  1. Facts sheet https://ods.od.nih.gov/factsheets/Thiamin-HealthProfessional/
  2. Thiamine deficiency in diabetes https://onlinelibrary.wiley.com/doi/10.1111/j.1742-1241.2011.02680.x
  3. effect of thiamine on exercise and performance https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073388/
  4. Low thiamine in plasma and cardiovascular disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1998885/
  5. High dose thiamine therapy for type 2 diabetes https://link.springer.com/article/10.1007%2Fs00125-008-1224-4

Diabetic Kidney Disease/Protein

Papers

  1. Protein intake and kidney function https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1262767/
  2. Prevention and management of DKD https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755100/
  3. Are low carb diets safe for DKD? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629514/
  4. Laboratory assessment of DKD https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4536646/
  5. Diagnosis, prevention and treatment of DKD https://www.aafp.org/afp/2019/0615/p751.html
  6. Which medications can protect heart and kidney https://www.ncbi.nlm.nih.gov/books/NBK492989/
  7. Effect of Keto diet on kidneys of diabetics https://journals.lww.com/co-endocrinology/Fulltext/2021/10000/Renal_function_in_patients_following_a_low.8.aspx

Articles/Videos

  1. Does protein harm the kidneys http://www.tuitnutrition.com/2018/08/protein-and-kidneys.html

Pancreas

Papers

  1. When do beta cells regenerate? https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6986204/
  2. Beta-cell dysfunction and insulin resistance https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608918/

Articles/Videos

  1. Re-awakening the beta-cells https://www.youtube.com/watch?v=I6sYsQqnPS0
  2. To grow new beta-cells, put the old ones to work https://www.youtube.com/watch?v=vOur5-fx8HE&t=3201s
  3. Beta-cells not permanently lost https://www.prnewswire.com/news-releases/insulin-producing-beta-cells-are-not-irreversibly-lost-in-early-type-2-diabetes-300864205.html

Lipids

Papers

  1. Dietary fat sensors https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4362267/
  2. Small LDL and heart disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441126/
  3. HDL as a marker for heart disease https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6651243/

Insulin and Glucagon

Papers

  1. Glucagon https://www.ncbi.nlm.nih.gov/books/NBK279127/
  2. I/G level and medications https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4801814/
  3. G/I ratio and a1c readings https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718759/
  4. Glucagon levels in normal and diabetic patients https://pubmed.ncbi.nlm.nih.gov/838198/
  5. Hyperglucagonemia and metformin https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871720/

Glucose-Ketone Index (GKI)

Papers

  1. GKI index and brain cancer https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4367849/pdf/12986_2015_Article_9.pdf

Articles/Videos

  1. Complete guide to GKI https://cancerv.me/2019/10/25/the-complete-guide-to-glucose-ketone-index-gki-tracking-for-therapeutic-ketosis/#what-do-GKI-numbers-mean

Glucose Control

Papers

  1. CGM in health patients https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2769652/
  2. Red meat and glycemic control https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850054/
  3. Glucose control in non-human carnivores and human diabetes https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847661/
  4. Hypoglycemia impairs tumors https://www.cell.com/cancer-cell/fulltext/S1535-6108(19)30152-7#%20

Articles/Videos

  1. Non diabetic and a CGM https://lilynicholsrdn.com/cgm-experiment-non-diabetic-continuous-glucose-monitor/

Oxidative stress

Papers

  1. Ketogenic diet decreases oxidative stress and improves mitochondrial respiratory complex activity
    https://journals.sagepub.com/doi/10.1177/0271678X15610584

  2. Acute oxidative stress and systemic Nrf2 activation by the ketogenic diet
    https://pubmed.ncbi.nlm.nih.gov/20594978/

(Bacon is a many-splendoured thing) #2

Wow! Thank you very much for this list. That was a lot of work!

I turned your post into a wiki, so that it can be maintained and updated. Anyone with a high enough trust level will see an icon that looks like a pencil writing in a checkbox; if you can see the icon, you can edit the wiki.

(Edith) #3

Yes, thank you!!! :smiling_face_with_three_hearts::pray:

(Mon Montierro) #4

Thank you!