Keto and local anesthetics

(Michele) #1

Has there been anything written about keto and how it ewlates to the efficacy of local anesthetics?
I’ve been to the dentist twice in the last month (1st and 2nd stages of a root canal) and found that the usual amount of local didn’t provide sufficient numbing. The last time I was at the dentist was prior to keto and numbing worked more rapidly.
So I’m curious about how being keto might affect something like the way in which a local anesthetic works. Also for that matter general anesthesia too.
Anyone got any thoughts or experience?

#2

Oh great, hope I don’t need any work done anytime soon, I already had a resistance to drugs before Keto (on average they have to double or triple the dosages for Me just to get it to kick in)

#3

It might be the condition at the current time. I’ve never had problems with local anesthetics at the dentist, but once when I had a more severe infection than the dentist realized, I didn’t get numb at all. It was the infection, not my WOE.

(You've tried everything else; why not try bacon?) #4

A dentist of mine years ago also said that it sometimes depends on how accurately the dentist can hit the right nerve with the novocaine. If the nerve for the tooth being worked on is in the middle of the bundle, it can be difficult to target. It’s not likely eating keto had anything to do with your experience.

(Michele) #5

Thanks. I’m eternally curious about the invisible biochemical influences and changes. I’m not looking for negatives; curious about potential reasons, answers, explanations. Those ah ha moments when something makes sense or is a reasonable answer to a question.

(Retta Stephenson) #6

Maybe, maybe not. I was told for years by my dentist that I was a “fast metabolizer”. He always had to re-inject me with more novocaine because it always wore off too fast. So, that makes me wonder about Keto and fasting. And how it revs up our metabolism during a fast??? Maybe at other times?? Just thinking out loud here…

(Kaiden) #7

Fascinating. I wonder if it’s the carnitine.

Autistics tend to have much higher anesthesia tolerance, but we also tend to have higher carnitine needs.

Then again, redheads and left handed people also tend to have higher anesthesia tolerance, so it may not be dietary at all.

(Retta Stephenson) #8

I’m also left-handed. I never heard that before; fascinating indeed. :vulcan_salute:

(Michele) #9

Not red-head or left handed. I do seem to have a high pain tolerence.

(Kaiden) #10

I’m not able to find much on the left-handedness. I heard this from my wife, regarding her ex-husband. His vasectomy sort of messed him up because they didn’t use enough anesthetic.

They didn’t use enough on me, either, but I wasn’t traumatized the way he was.

I’m not sure if it’s circulation differences or neuroanatomy.

#11

I had to have a crown recently and noticed nothing unusual about the novacaine. It lasted for hours after.

(Hayley White) #12

Had same problem this week 2 parts of root canal. Dentist was surprised how quickly the novacaine would wear off on me. I would be completely numb and after 30 minutes I would jump. Ouch felt that. He would numb me up again and it would work for a bit.

(Tamara Newsock) #13

Yes. If you’re in a state of nutritional ketosis, your blood is acidic. Local anesthetics are bases. For them to bind to the sodium channels to induce numbing more local may be required per the Henderson hasselbach equation and knowing drug pka values.