I urge caution in interpreting this, especially as it's not OA, but: in PsyPost, «Surprising Alzheimer’s breakthrough: Sugar in neurons might be the missing link»

(Ellenor Bjornsdottir) #1

Here’s the article: https://www.psypost.org/surprising-alzheimers-breakthrough-sugar-in-neurons-might-be-the-missing-link/

And I cite the underlying publication: Bar, S., Wilson, K.A., Hilsabeck, T.A.U. et al. Neuronal glycogen breakdown mitigates tauopathy via pentose-phosphate-pathway-mediated oxidative stress reduction. Nat Metab 7 , 1375–1391 (2025). https://doi.org/10.1038/s42255-025-01314-w

It’s not open access, but I’m sure those who want to look into the matter either have money, institutional access, or their means of going about this.

I haven’t even been on a ketogenic diet for quite some time (call it bread addiction, call it whatever), and neither have I been on these Forums, but I saw this, and I thought of the community here.

(Bean) #2

Sometimes academic articles can be had through an inter-library loan. Worth checking for those who don’t have automatic access.

(Cathy) #3

More evidence of what has been called type 3 diabetes from glancing at the article. It seems there is more and more science pointing to this. Thanks for sharing.

(Joey) #4

It would be hard to imagine how eating a large amount of a particular category of foods (i.e., dietary sugars) can be so toxic to one’s long term health and disease-inducing across so many body tissues and organs … yet somehow not cause damage to one’s brain, too?

While I’m heartened to see these results (skimmed it), they add a little more confirmation to notions so many of us have already embraced. :brain: