I don’t use artificial sweeteners.
I saw this article from Dr. Perlmutter about the use of artificial sweeteners.
Perlmutter quotes the study:
…to weight gain and worsening glucose tolerance by inducing dysbiosis and altering the composition and function of intestinal microbiota. The altered microbiota exhibit enhanced energy harvest pathways previously associated with obesity in mice and humans.
The study says:
Evidence from a rodent study
indicates that chronic saccharin consumption contributes to weight gain and worsening glucose tolerance by inducing dysbiosis and altering the composition and function of intestinal microbiota. The altered microbiota exhibit enhanced energy harvest pathways previously associated with obesity in mice and humans. These mice also had altered bacterial taxa similar to those found associated with type 2 diabetes in humans [42, 43]. Other low-calorie sweeteners such as sucralose has also been shown to contribute to weight gain and altered intestinal microbiota in rats [44]. Low-dose aspartame, however, was associated with altered intestinal microbiota with worsening glucose tolerance but less weight gain in rats when challenged with high fat diet [45]. The underlying mechanism is unknown and warrants further investigation
So, the results apply to rodents, but I don’t believe this was studied in humans. Nevertheless, I believe that artificial sweeteners are not good for optimal weight loss.