I’m fascinated by this question! In my own experience, when I use Splenda or consume a product containing Nutrasweet, my demand for insulin doesn’t increase (ie I don’t need to take any extra insulin to cover it).
I totally get how artificial sweeteners can stimulate desire for, and consumption of, other sweet things - whether or not this is ‘want’ from the taste buds or the brain or indeed the pancreas, I don’t know, but it does seem to be a ‘thing’, whatever the reason, be it physiological, endocrinological or psychological.
I’ve never had cause to be tested for insulin response - well actually as type 1 I have zero, so that’s a non-starter! - and I know we’re all different anyway in terms of our bodies’ responses to, and demands for, things - but I know there’s a lot of debate out there as to whether artificial sweeteners stimulate an insulin response, and I find it very interesting!