Fasting, Coffee & Tea and Autophagy

(Eric - The patient needs to be patient!) #1

Low Carb Breckenridge 2018 - Q&A Day 3 Morning Session

I just love the Q&A sessions with all the low carb conferences. I learn so much from the Q&A. In this one, Megan Ramos talks about fasting a fair bit. She mentions at least twice that much more research needs to be done on the topic of Autophagy. Near the end, she mentions that she is uncertain to what extend coffee and tea during fasting affects autophagy.

I’m wondering if anyone has seen any research on this topic? I’m 65yo and want the benefit of autophagy. To-date my fasts have been IF 18/6 and 22/2. Getting ready to do a 42 hour fast next week. Hopefully 2 of them. I drink black coffee and a variety of green and black tea during my fasts. All the coffee and tea is unadulterated.

Wha say you?

(Bob M) #2

It’s unclear where autophagy starts. Some say not for multiple days of fasting. I just listened to this:

And he said any calories at all (such as from coffee) might stop autophagy.

Personally, I use black coffee, tea, and herbal teas when fasting. It’s hard enough to fast for multiple days, and I can’t see doing a water-only fast, which would require my quitting coffee and also drinking only water.

He also said dry fasting for 24 hours has more benefits than much longer water fasting.

#3

I would highly recommend the podcast that Rhonda Patrick did with Valter Longo. I’ve been in this space for a long time and didn’t think I’d hear too much that I wasn’t familiar with, but I found it fascinating and full of new information.

(Eric - The patient needs to be patient!) #4

Madeleine

Thanks - I’ll put that on my list for the commute home today.

(Eric - The patient needs to be patient!) #5

I found this study that suggest, at least in mice, that autophagy is stimulated by coffee consumption even without nutrient depletion. https://www.ncbi.nlm.nih.gov/pubmed/24769862

Yes I know this is in mice.

This epidemiological study found an inverse relationship between coffee consumption and all cause mortality (except cancer) in humans. Since this is a epidemiological study it is a correlation and not causation result.