This passage is in quite a few fluffy articles: “There’s compelling evidence showing that when you supply fuel to your mitochondria at a time when they don’t need it, they leak a large number of electrons that liberate reactive oxygen species as free radicals.”
Can anyone recommend a source to support this? … or even good articles or studies on the topic?
Sure they do, if you give them glucose.
Biochemically, burning fatty acids are cleaner than sugar.
My pleasure!
What surprised me the most read that is that I was like most when I saw Lustig’s lecture on Fructose and vowed from that moment on to never touch the stuff, but I see that Feinman would like to put the brakes on the feverish fructo-phobia, and lays out the metabolism of fructose in easy to understand terms. Easy, just not simple.
There is a path for it to get metabolized, it’s not some alien compound that our cells don’t know what to do with except to turn it to fat and dump it in the backyard of the liver.
But yes the dose makes the poison in any carbohydrate’s case. I’ve never seen any upper limit you should impose to fat intake period. Your BMR apparently will shift into a higher gear and burn off what ingested fat it can and if there’s too much, it’ll tuck it away. Still earning all about that myself, how adipose tissue will uptake excess energy while at the same time in a low insulin environment be open to mobilizing other fats. I’ll have a better handle on it when I commit all the different hormones to memory as well as their action at different physiological levels of macronutrients. Ain’t got time for all that at the moment. 
Good, informative post.
There is so much to learn and of such great interest. I need to quite posting and spend more time reading.
Keto for Life!
Richard