This is a new video from 2017 low carb conference. Some main points:
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White fat is inactive, associated with energy storage
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Brown fat has lots of mitochondria and is metabolically active, tends to be associated with heat generation (it actually burns glucose, just like muscle) and increase of metabolic rate.
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Obviously you'd prefer brown fat rather than white fat if you want to keep trim.
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Insulin moves our fat towards white fat.
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Ketones move our fat towards brown fat.
The above factors may give a benefit for the keto diet, since it will move us towards more brown fat and therefore higher metabolic rate. It makes the CO part of CICO difficult to analyse without looking at the hormonal factors.
Another thing missed by CICO when comparing Keto to other diets is that the ketones tend to be excreted in urine and breath (a calories out mechanism)âŚanother example where Keto may provide a benefit on the CO side that is not easily recognized by traditional CICO view without considering hormones.