Diet Doctor Podcast #35 — Ben Bikman, PhD

(Eric - The patient needs to be patient!) #1

Another great Ben Bikman podcast interviewed by Brett Scher. covers I/G ratio, autography, fasting (a little), gene expression for burning glucose in the brain of dementia patients and more.

Published today 12/7/19 or 7/12/19 as you would have it.

(bulkbiker) #2

One of the best I have seen Ben is a true superstar.

(Troy) #3

Interesting listen
Thanks!

Talks about the Glucagon vs Insulin Ratio
Fascinating

More here:

(Troy) #4

Happy 3 year Anniversary!
:slightly_smiling_face:

(Bob M) #5

I’m about 1/2 way through this, and it’s again excellent.

I really like the idea about glucogon resistance and alpha cells being messed up. I must have a normal glucagon response, as I can eat as much protein as I want and experience no change in blood sugar whatsoever. Meanwhile, someone with poor glucagon response (due to messed up alpha cells) could have high blood sugar (over-reactive glucagon) or even low blood sugar (under-reactive glucagon) due to protein. And the glucagon resistance concept could explain why some have such a bad time fasting, while others (like me) typically do not.

Maybe my system isn’t as messed up as I thought it was? There are obviously others out there with issues much worse than mine.

I’m thinking of getting glucagon tested. Will have to research how much that costs…

(Eric - The patient needs to be patient!) #6

Let us know. I don’t seem to be sensitive to protein. I need to do more BG measurements however. Might just do that now because I just had 8 oz Ground Beef and 4 oz of stewed pork.

Also I can fast easily. But you probably knew that!

(Eric - The patient needs to be patient!) #7

BG 83 mg/dL about 30 mins after the meal I just listed.

(Bob M) #8

That looks great for blood sugar results.

I also thought his idea that there is no such thing as physiological insulin resistance was interesting. I always think of this as (partly) causing the morning blood sugar rise I get. I also think of this as an exaggerated effect for low carbers who eat carbs. I’ll have to rethink that. In particular, I don’t seem to have an exaggerated effect due to carbs, though honestly maybe I do and just don’t know it (since I never eat high carb to see what my response would be after eating high carb for a while).

#9

Excellent podcast.

I enjoyed that Prof Bikman asserted his understanding that low carb eating creates a true glucose intolerance, rather than a physiological insulin resistance that can result in LCHF eaters doing poorly in glucose tolerance testing.

I wondered if the synergy between the human and the gut biota is altered. That the carb eating gut biota go quiescent while the fat eating biota respond to the increased dietary fats?

@atomicspacebunny Bunny has often alluded to this, this loss of an ability (albeit temporarily) to digest carbohydrates once a person goes long-term keto or carnivore. i.e. a loss of dietary flexibility.

(Bunny) #10

Dietary flexibility which is better?

I am thinking when it comes to the upper intestinal tract that is where our proteins and fats are needed for bile production etc.

But the lower intestinal tract needs resistant starches (not a carbohydrate for the human body, it is gut bacteria carbohydrate) so that it works synergistically with the upper intestinal tract.

That is why people get SIBO and IBS because one is getting the proper nutrients and not the other so you get this dysbiosis occurring where your feeding a set of microbes that start to infiltrate the upper or lower where they don’t belong?

Gut microbes also produce the same endocrine hormones our internal organs do, so if they are not getting fed or they start to die off you can get an endocrine dysregulation if your internal endocrine start to fail.

Some people have even experimented with resistant starch or buytrate enemas[1] but if your only eating meat and fat your ignoring the lower bowel?

You did not cure your intestinal problem by only eating meat and fat although it may seem like it temporarily; what your in fact doing is setting up your colon for further damage down the road with feeding only amino acid eating bacteria that damage the micro-RNA inside the colon cells which lead to future intestinal cancers and once it starts to metastasize it can cause different types of cancers through-out the entire intestinal tract or other parts of the body.

All because one did not add resistant starch to their dietary regimen and make sure their iodine levels are adequate; because they want to play the Neanderthal Cave Man social game on YOUTUBE?

Footnotes:

[1] “…So much so, that investigators are using oral butyrate supplements and butyrate enemas to treat inflammatory bowel diseases such as Crohn’s and Ulcerative Colitis. permeability. In tissue culture and live rats, butyrate causes a large and rapid decrease in intestinal permeability. …South Denver Cardiology

Note: intestinal permeability are your histamine intolerances and auto-immunity disorders and the anti-bodies that are created, the longer you remain permeable that attack your own body parts. Whatever your eating goes directly into the blood stream through broken junctions in the gut or the smell of chemicals can cause this also when you have thin mucosal barrier teaming with gut microbes in your intestinal tract to protect you from the outside world.

(Bob M) #11

I personally love Dr. Bikman’s philosophy. I particularly like that when someone criticizes his view on saturated fat, he shows them the studies and asks them to find contrary evidence. They shut up after that.

Also, he addressed mTor and the fact that while protein does cause some release of mTor, high carb causes greater release for much longer. Protein is not your enemy.

I like how family-oriented he is. (Though I assume he’s Mormon, which means this is built into his religion.)

(Eric - The patient needs to be patient!) #12

For me that is okay. We all come to different places different ways. Family is my bed-rock. For the record I am not mormon.

(Bob M) #13

In a different interview, he made the observation that he was speaking with someone who just wanted to bench more (which I did too, when I was younger). He remarked that his training was centered around his family, to enable him to resist injury and be the healthiest he could be for his family. I thought that was an interesting way to look at exercise.

(Edith) #14

That’s one of the reasons I exercise, as well. Also, to look HOT for my hubby. :smiling_imp: