So? The metabolic milieu is still catabolic, and the tone is being set by glucagon, not insulin. I’ve watched Ron Rosedale’s videos, and I’m not convinced that his picture of mTOR activation is the whole story. But I’m not claiming that we need a lot of protein in our diet, merely that we don’t need to fear it.
It is very hard to eat too much protein, in any case. I seriously doubt most people can get to the point of overwhelming their uric acid cycle—it’s very hard to eat that much food. If Raubenheimer and Simpson are right about their protein-leverage hypothesis, then most people aren’t going to want protein past a certain point—they would have to force themselves to eat more.
But some people seem to need more protein in proportion to fat, while others need more fat in proportion to protein, and I don’t see the point of telling everyone to observe a hard limit. After all, our ancestors over the past 2,000,000 years seem to have done all right, and I seriously doubt that when feasting on mammoth or aurochs or whatever, they bothered to figure out their lean body mass and how many grams of protein they needed to eat in relation to it.