Bone broth anti ketogenic?

#21

I make bone broth almost weekly but my girlfriend drinks it all, hahaha I usually have a 1-2 bowls a week. It’s keto for the minerals but I don’t understand why people guzzle the broth and ask why it kicked them out of keto, when zero’s 0g’s of fat and 99% of the macronutrients come from protein.

(Cathy) #22

I have read Dr. Ede’s blog on that subject and I believe she made it understandable for the average person (i.e. me). I also read Travis Christofferson’s book and that was a bigger challenge but well worth the effort.

(Toni Peter) #23

Mind = blown! I have to try this!!

P.S. I’m morbidly curious if this has ever been done on Criminal minds or the like…

#24

Hadn’t thought of Criminal Minds Episode with bones cooked to the max. Maybe we should suggest it for a show! LOL. Hope it works well for you.

(Michael Wallace Ellwood) #25

That’s a new one on me. I thought the ketones were a by-product of fat metabolism, and didn’t come from protein.

If it’s 1st year biochem, could you please explain the biochemistry of the conversion of protein to ketones for me? Thanks.

In this article:
https://proteinpower.com/drmike/2007/05/22/metabolism-and-ketosis

Michael Eades says:

The liver requires energy to convert the protein to glucose. The energy comes from fat. As the liver breaks down the fat to release its energy to power gluconeogenesis, the conversion of protein to sugar, it produces ketones as a byproduct.

…which sounds a little bit like what you are saying, but isn’t. The ketones in that sentence are coming from the fat, not the protein (if I understand him correctly).

#26

I agree, I’ve never seen anything to suggest that ketogenesis runs on the amino acids from protein and is entirely the product of fat metabolism.

#27

A ketogenic amino acid is an amino acid that can be degraded directly into acetyl-CoA, which is the precursor of ketone bodies [emphasis mine]. This is in contrast to the glucogenic amino acids, which are converted into glucose. Ketogenic amino acids are unable to be converted to glucose as both carbon atoms in the ketone body are ultimately degraded to carbon dioxide in the citric acid cycle. https://en.wikipedia.org/wiki/Ketogenic_amino_acid

There are only 2 amino acids that can’t be converted into glucose, Leucine and Lysine.

(Patrick B.) #28

Correct, however, not the whole story. Tryptophan, phenylalanine, tyrosine, isoleucine and threonine are both glucogenic and ketogenic.

(Michael Wallace Ellwood) #29

Thanks @carolT and @Faitmaker.

I’ve done a reasonable amount of chemistry including a lot of organic chemistry, but never (formally) biochemistry. I am picking up bits here and there though. :slight_smile: I have “The Chemistry of Life” by Steven Rose, but it has a few holes (such as lipoproteins). “Biochemistry” by Jeremy M Berg et al looks tempting, but at over 1,000 pages, I’m not sure if I could lift it, let alone read it.

(and I happened to read a blog posting by Chris Masterjohn in which he was highlighting a mistake he’d found in it. He wasn’t really criticising textbooks though. Knowledge is always changing, and it’s impossible for them to keep up, so (I think he was saying) use them for the basics and then try to find online any new stuff in areas of particular interest).

(Sam Marcos) #30

Richard, sorry for the of topic message. I haven’t figured out any other way to message you. Is there any way you can cancel my accounts? I’d like to use the “sign in facebook” option.