With all the talk out there lately on Allulose, I have started adding about a teaspoon with my morning tea. Interestingly, I just used my KetoMojo and my glucose was 53, but my ketones only at .6.
I’m not worried, just find this interesting. I’ve been following a Keto diet since 2018, so I suspect my body is burning ketones, so they aren’t very high. I feel fine, so, no big deal. Just thought someone else might find this interesting. 
That is interesting. Have you compared days with allulose (which I can never remember how to spell – how many l’s are there?) and days without?
53 is an impressive morning glucose. Mine is typically above or near 100, or was in 2017-2019:
That wasn’t first thing in the morning, that was mid morning after I had had the tea with Allulose. From time to time I check first thing in the morning and it is usually into the 90’s with .2 or .3 ketones. When I have tested later in the day my glucose comes down into the 80’s and ketones don’t get above .4. It’s been frustrating.
I tested yesterday and again today with similar readings and thought it interesting. I just wondered if this is normal and if anyone else has tested Allulose. I suppose it could be something else and not the Allulose. Anyway, just thought I’d share.
I’ll keep testing the next few days to see if this is what always happens, or if it changes.
Just tested again today, Sunday morning 6-16-24 at 7:50 am. I had a cup of black tea with a teaspoon of Allulose. KetoMojo says my glucose is 54, but shockingly, ketones are only .2. so a GKI of 15 and KetoMojo says I am not in Ketosis. But I feel fine, so I must have low ketones because I am using them.
I really should have checked my glucose before I drank the tea. I’ll have to do that next time. I am doing fine because I have been eating this way for years. I’m going to test again in a few minutes. I find this stuff interesting.
Mostly, I have been slowly gaining fat again, even though I keep my carbs below 20 and I want to change that. My thoughts are that I’m just eating too much fat or that the Zevia drinks I have been enjoying have raised my insulin just enough to cause fat storage. I have been eating more fatty meat and it is hard to give up the fatty cuts.
Anyway, I need to test more and see how things affect me. I have cut out the Zevia drinks except for with a meal. I hadn’t realized how much I had been craving the sweet taste and realize that this may have had an effect on my health even though they seem fairly “clean”.
More later.
Interesting. I walked around a bit, went outside to chase the squirrels off the bird feeder (futile), and came back inside. Tested again and my glucose is up to 88 but ketones are still at .2. My liver probably made glucose because I was moving around. Wish my ketones would go higher, but I’m probably using them. Hummm…
Allulose is known to block sugar(glucose) receptors and probably transporters. This has the effect of lowering blood sugar.
Yes, I’ve seen a number of YT videos discussing this effect. It sounds promising.
I’ve been wondering about it’s effect on those of us on a Ketogenic or Carnivore diet. I think it can also have an effect on insulin, but I don’t know if that lasts long term or just initially or even if it is enough to cause fat storage or not.
I did add some Allulose to a non-Keto cinnamon coffee cake that my husband and sons like. They don’t do Keto, especially not my husband. My sons are probably more low carb, but not Keto.
Anyway, I used the Allulose in the cinnamon sugar topping of the coffee cake with the hope it would reduce the impact of the flour and sugar on them. One of my sons told me that it made him feel sick to his stomach and that he felt weird, (I suspect he had a large piece), so I hesitate to add it to anything non Keto that I make for them. Also, I wonder if it might lower MY glucose too much since my glucose is already lower than someone on a SAD diet.
Anyone have any experience - any N of one experiences or any articles that discuss this?
I’m still exploring Allulose. 
Nicholas Norwitz PhD says here, about 6 minutes in that Allulose causes no glycemic and no insulinogenic response so it won’t spike glucose or insulin, but is an important inducer of GLP-1: https://www.youtube.com/watch?v=pr93EsEV2bM
Interesting.
You know, I really hate instagram videos. How do I rewind? He cites to a paper, and it blows by the paper so fast I can’t get the title. But I can’t go back. There’s no slider at the bottom. The same thing happens on my phone. I’ve given up on Instagram because of this.
Edit: had to watch the video the whole way through, then it restarted. Here’s the study:
It’s in rats, though.
Bob, thank you for sacrificing your time to get to this study. I appreciate it!
It sounds like Allulose, assuming this works the same in humans, would be great for type 2 diabetics. I’m curious about how it affects those of us who have been on a Ketogenic or Carnivore diet for a long time, and thus already have low blood glucose. I’ve used it in Keto deserts and treats from time to time, but I don’t think I ever tested my glucose after using it.
Guess I am also wondering if I’m the only person who has had really low blood glucose after adding a bit in a morning tea or coffee. I would be less concerned if my ketones where higher, but I suspect they were low because I was needing to use them more.
FYI, I did check my glucose and ketones this morning before drinking the tea, but it was about 30 minutes after I woke up. My glucose was 79, and my ketones were .2. Not very impressive ketones. 
Last night my wife used allulose(RxSugar) to sweeten a coconut cream topping she made for a cherry pie she had bought for my father’s day. I loved it. I have used it some in chocolate as well. I have never noticed a side effect… but then I have never had a side effect with xylitol or erythritol/monk fruit either… other than maybe a little extra gas with erythritol. I think the erythritol gives my dad lots of gas, but I don’t seem to be much different. I notice no difference with allulose, and believe it to be safer in large amounts than the sugar alcohols. Again, I use stevia to sweeten any drinks I want sweetened.
So, I have been noticing for a while now that if I eat Lily’s chocolate chips, I get stomach issues including gas, which I don’t get eating normal chocolate (chips or bars). (My wife buys the Lily’s for her, but I eat them sometimes.) I’ve been wondering if it’s the erythritol, and this is one reason I started using allulose instead for anything that’s “sweet” (which right now is mainly puddings from Maria Emmerich).
I have blood sugar strips, so it’s possible to test what happens for allulose. My main problem is that I only eat allulose in puddings, and I eat those only at night before bed. I’'ll be lucky to get a blood sugar before eating and at most one afterwards. That might not tell me much. And ideally, it would be nice to have a “comparison”, like pudding made with no sweetener (or another sweetener?). It’s not an easy thing to test for me.
This video mentions Allulose, watched it a long time ago) but the point is that with some of the sweeteners, the glucose numbers went down but the thought is that this is because insulin went up and forced glucose down. Ideally you want a sweetner that neither pushes glucose up or down
https://www.youtube.com/watch?v=CYfqvTZWilw&ab_channel=KetoConnect Allulose is around 4:30
Thanks for that link! I do remember seeing that YT video a long time ago, but don’t remember it. I’ll re-watch it. Thank you!
Dr. Dom D’Agostino says there is a cumulative affect from using Allulose every day in this video: https://www.youtube.com/watch?v=FsUlYB-AolY It’s been a while since I’ve watched this one, but I have watched it several times.
Hmmm…they also said they got the worst gastrointestinal issues due to allulose. That’s weird for me, because it doesn’t seem to cause me any issues. But I’m also not eating just the sweetener.
We really need a pin-prick insulin tester. Because if blood sugar goes up, there should also be an increase in insulin at some point, to bring blood sugar back down. Conversely, if blood sugar goes down, which happened with allulose according to them, it’s possible for insulin to have gone up. Is one of these worse?
If you look at protein for instance, protein going up causes insulin to go up, but there’s no blood sugar decrease. Why? Because any insulin that could cause blood sugar to decrease is counter-acted by glucagon. Why doesn’t glucagon counteract the blood sugar decrease created by allulose too?
The original insulin versus glucagon lecture:
Dom (easiest to type) says that keto diets can help produce GLP1 (the hormone by wegovy, they activate the receptor), via the intestine releasing “something” that acts through a pathway. Allulose does something similar.
Here’s the paper:
https://www.nature.com/articles/s41467-017-02488-y
Dom says that allulose can impact glucose control, and enhance insulin secretion but also insulin sensitivity (to a greater extent than secretion). GLP1 agonists are effective obesity drugs but have side effects. D-allulose does not cross the blood-brain barrier, work on L cells in gut. Allulose causes a release in GLP1, abolishes the hyper-phagic response in mice during the light period. On paper, allulose looks remarkable. Vagal network is involved. Talks about a bunch of peptide hormones. Allulose suppresses food intake. They use a tube feeding to give precise allulose (into mice). 1-2 grams/kg is what they used. 20-60g of allulose a day. He said allulose by itself can cause GI distress, but the bars he was eating did not. He was eating 1 bar per 6 hours, each contained 10g allulose. His glucose went down when he ate a bar. They discussed dosing comparisons between mice and people. He thinks you could get what they were using. He seems to be a fan. Lowers ghrelin and leptin. Lowers A1c. Human trials with it too. Can cause GI upset but need about 50g/day. Low fodmap. 20-60g/day caused 500 percent increase in GLP1 secretion within a short time period (hours), came back down. He thinks allulose could cause a decrease in eating.
Seems to reduce glucose:
They were all thinking this could help with adding some sweetness, while at the same time potentially decreasing eating. He thinks it alters the endocrine system in a favorable way. He says it has an insulin-enhancing effect, where insulin was lower overall after 11 days. Could possibly improve brain metabolic health. Could be the most well-studied replacement sweetener.
Edit: I thought they were going to the next study (about fructose), but they weren’t. They have human studies of carbs or carbs + allulose, and the post-prandial rise in glucose was lower with allulose. Allulose facilitates glucose disposal when you exercise.
Interesting. The only thing that gives me minor distress are Maltitol and sorbital. A family member cannot tolerate erythrotal well but I seem to have no problems. I have not used allulose enough to know (bought some liquid a year ago and still have a little left).
I had wondered something that I was going to post about. If I get very stressed I cannot eat. I may have a bite but it is physically difficult for me to sit down to a meal (I am talking very stressed, potentially life or career changing consequences or hosting a major event for the first time, not minor stress like recently I had to change of my kid’s flights at the last minute (which resulted in me eating something I was not supposed to), they were in a safe place, it was stressful but I knew it would be fine but I needed some chocolate after that). In the mega stress situations I have no appetite. I would imagine, minus the stress, this is how people feel on the Ozempic etc. I find I lose much more weight in those situations than I do if I simply fast for a few days. I wonder if there is a different mechanism? That the lack of appetite is by itself helpful for weight loss
My husband is on Ozempic and no, it’s not just feeling less hungry or distracted. Post injection he’s often a bit nauseous, and he often gets uncomfortably full on much less food. A lot of the appetite suppression may be due to gastroparesis - very sluggish digestion.
