Why are there no obese 90 year olds ? (Insulin and Aging)

aging
(VLC.MD) #1

Random thoughts on age and insulin.

Q: Does your pancreas’ ability to produce insulin simply just go down over time ?
Type I diabetics can’t make insulin at diagnosis and they lose weight like crazy. Or a Type I that just stops injecting they lose fat like crazy.

As the pancreas slows down it’s ability to produce insulin … does that explain the weight loss that occurs with age ? or do the bowels change ? or appetite ? or all of the above ?

Older people exercise less (on average) … but tend to lose weight …

What are body composition changes that come with age ? I guess we all lose muscle and get more percentage of fat. Is that related to the body’s hormones ? or ability to make muscle ? or lack of exercise ?

Will there be overweight / obese 80-90 year olds in the future ? (ie. people are just heavier now than they were a long time ago ?).

Any random comments on aging and insulin ?
I read this … age is associated with hyperinsulinemia.

Researchers needed !

Insulin causes Aging

Tatar’s research is part of a growing body of evidence linking low insulin levels to increased longevity. In recent years, scientists have found that mice and other animals live longer when they eat a low-calorie diet, which reduces insulin production.

(Donna ) #2

I just figured that obese people die from complications before they can make it to their 90’s, not that they improve and were all slimming down in their 90’s.

(Duncan Kerridge) #3

My grandmother got to 90, she was very big my whole life, no major health issues as far as i’m aware. But around 85 she lost weight rapidly, not through any of her own good intentions I might add. When she died she was normal weight, skinny even,it was quite a strange transformation to witness.

(VLC.MD) #4

That’s exactly what I am talking about.
You had a dramatic case.

I want to know what causes that.

Is it a lower beta cell mass that doesnt produce insulin as well ?

(Duncan Kerridge) #5

I wouldn’t be at all surprised if that was the case. She continued her crappy diet but her body didn’t store the energy instead it ate it’s own fat which sounds like it must be related to insulin.

(KCKO, KCFO 🥥) #6

Lots of fat Texan are long lived, 90 and beyond.

(VLC.MD) #7

There must be.

I’m mostly interested in the natural weight loss that comes with age.

#8

My grandmother died at 98 and was living alone without any help until 95. She was always stocky, overweight but not morbidly obese. She hated vegetables, never exercised but lived in cities and never learned to drive, loved meat and scotch. Right before she died I went out and got her some liver because she wanted someone to make her liver and onions and her caretaker was willing. She also smoked for a number of years but quit. She did develop minor diabetes in her late 80s but did not require much medication if any. She could carry on a very intelligent conversation almost up to the end and had perfect recall.

Her sister who loved fruits and vegetables and would rarely eat meat because she did not want to pay (lived in a warm climate so vegetables were cheap) and lived in a 4th floor walkup died from complications of a heart attack at age 76. Her sister was always a little heavier but not much. My great grandmother who was always thin died at age 78 of a heart attack.

When my grandmother died she was under 5 feet (about 5’4 at age 30) and weighed at least 160.

My husband’s grandmother was 99 and stocky, heavy by BMI standards but his family is very muscular, even the women. developed severe dementia in her early 90s and she no longer recognized H by the time she was 95

My MIL’s best friend is morbidly obese and about 83 years old. Has always been that way. Has some knee and mobility problems but otherwise is very social and busy

(Bunny) #9

Was thinking about your question, I am certain excessive glucose over long periods of time with no break in the mix and duration of insulin spikes in the blood stream is what causes diabetes and so I decided to write some of my thoughts on some of your questions!

MORE THAN LIKELY CAUSES OF OBESITY EXOGENESIS:

EXOGENIC (external supplementation) CAUSE AND EFFECT LOOP CYCLE OF ENDOGENIC DORMANCY & SUPPLEMENTING (eating/ingesting) THE NATURAL HUMAN ENDOGENIC PHYSIO-CHEMISTRY WITH EXCESSIVE EXOGENIC SUBSTANCES:

SUMMARY: eating/ingesting plant based sugar doubles the amount of glucose (sugar) in blood stream at many given frequencies. Duration cycle loop of its (excessive glucose) presence vs. lack of physical activity and resistance exercise to utilize (burn) excessive glucose? i.e. a break from the excessive amounts of glucose circulating in the blood stream decreasing excessive insulin spiking.

SYNOPSIS:
Metabolic physio-chemical, immunological suppression and cellular damage as it relates to recovery time due to the presence of excessive exogenic sugar intake including endogenic glucose (gluconeogenesis from fat, protein and carbohydrates; including highly refined and processed carbohydrates) and reoccurring insulin spiking time loop duration…

SUGAR:
Plant based sugar (glucose, fructose, and galactose) theory? is a crystalline particle or substance that acts as a shield or barrier (e.g. blocking/inhibitor to trace mineral and vitamin absorption) to other substances. In scientific literature it gives the following description: “…The acyclic mono- and disaccharides contain either aldehyde groups or KETONE GROUPS. …,” “…In these closed-chain forms, the aldehyde or KETONE group REMAINS NON-FREE, so many of the reactions typical of these groups CANNOT OCCUR. …”

Exogenic plant sugars activate neuro-chemical behavior that releases very excessive amounts of dopamine (nucleus accumbens) i.e. a highly addictive and abused substance occurring in nature.
-vs-
Endogenic (gluconeogenesis from FAT, PROTEIN (i.e. CARBOHYDRATES; and also highly refined/processed) glucose. i.e. body DOES NOT cease endogenic production through supplementation (carbohydrates) and left over (excessive) sugar (glucose) is stored in muscle tissue as glycogen and the rest stored as FAT; Ketosis reverses this process.

DORMANCY EXAMPLES:

Example 1.
Methamphetamine bio-neuro-chemical conversion (mimic) of serotonin and dopamine i.e. body and brain ceases (temporary) endogenic production.
-vs.-
Endogenic serotonin and dopamine.

Example 2.
Exogenic Steroid Hormones i.e. body and brain ceases (temporary) endogenic production.
-vs-
Endogenic Testosterone and Androgen (testicles [primarily] ovaries & adrenal glands)

Example 3. DEHYDROEPIANDROSTERONE or DHEA supplementation i.e. body and brain ceases (temporary) endogenic production.
-vs.-
Endogenic DHEA (testicles, ovaries, adrenal glands [primarily] & brain)

Example 4.
Exogenic HGH i.e. body and brain ceases (temporary) endogenic production.
-vs.-
Endogenic HGH (cells on pituitary gland)

RESEARCH ANALOGY FOR TIME DURATION LOOPING CYCLES & FREQUENCY:

Excessive Exogenic Blood Glucose (Sugar)?

how long (duration): ________.

frequency (how often?): _______.

Ibid. Insulin Spiking?

how long (duration): ________. .

frequency (how often?): _______.

RECOVERY TIME (from High Carb; refined/processed) & High Plant Sugar Intake?), KETOSIS and/or INTERMITTENT FASTING (AUTOPHAGY & APOPTOSIS)?:

how long (duration): ________.

frequency (how often?): _______.

How much damage (temporary or permanent) to metabolism is being done by glucose insulin spiking (bodies physio-chemistry and cells) in relation to duration of time and frequency factors?

[important caveat: this text is a working primer of my personal paradigm notes and subject to omissions, mistakes or errors.]

(VLC.MD) #10

More data for you.

The human body contains approximately 5 liters of blood. This amounts to 4 grams of sugar in the blood, which is less than a teaspoon of sugar!

The American Diabetes Association draws the line between a healthy individual and someone being pre-diabetic at 100 mg/dl. This 100 mg/dl amounts to about 1 teaspoon.

For someone to be diagnosed as diabetic, her fasting blood sugar is over 126 mg/dl. For this person, the amount of sugar in her body is about 1 ¼ teaspoons.

This tells us that the amount of sugar is very carefully regulated: the difference between being healthy and being diagnosed as diabetic is a quarter of a teaspoon of sugar.

An extra-value meal at McDonald’s, for example, 2 cheeseburgers, a large order of fries, ketchup, and a coke. This amounts to 230 grams of carbohydrates which converts to 230 grams of sugar, or about 46 teaspoons of sugar. That’s putting in your body 46 times the amount of sugar required to maintain a healthy blood sugar level.

Source:

To funnel 230g sugar via a place that normally has 4g of sugar is quite a bottleneck ! I dont think your body appreciates it !

(Bunny) #11

AMERICAN DIABETES ASSOCIATION is killing people with what they recommend in carbohydrate intake! Not unless your pumping iron like a body builder everyday or exercising likes there is no tomorrow?

McDonalds and most fast food establishments puts too much sugar in everything!

(VLC.MD) #12

Good article here.