There are some webpages arguing along the following lines:
Does Hot Water Destroy Whey Protein?
Hot water, below 100 degrees celsius, can cause denaturing which impacts the whey protein’s ability to dissolve in liquid. However, it does not impact the benefits the protein provides when consumed.
If you’ve ever googled why your protein powder gets clumpy in hot water you may have uncovered that heat causes whey protein to denature. This can sound a bit alarming and lead you to wonder whether that whey protein is still just as beneficial to consume. Lucky for you, the answer is no, heat will not destroy the whey protein. Let me explain further.
When whey protein is exposed to high heat, the outside structures of the protein molecules will unfold and aggregate together. This is just a fancy way of saying the molecules will clump together. Research shows that below 100 degrees celsius, these changes are purely cosmetic and do not impact the nutritional benefit the whey protein provides.
Above 100 degrees, there can be some further changes that slightly impact the whey’s nutritional benefits, however, this is nothing to be concerned about. These changes are quite minor and similar to what happens when you cook other protein sources.
It’s also important to remember that you aren’t likely to find your whey heated up to above 100 degrees unless you are baking with it. If you are simply mixing whey with hot water you will be well below this threshold and have nothing to worry about.
https://feastgood.com/whey-protein-with-hot-water/
But I would like to know for sure.