Nothing, Insulin isn’t our enemy, quite the opposite, our enemy is chronically high insulin when it shouldn’t be. In keto circles we refer to insulin as the “fat storage hormone”, but it’s also what transports nutrient into cells as well, which is why in bodybuilding for decades people spike their post workout drinks with dextrose or maltodextrin to drive post workout nutrition into the muscles more efficiently, and it absolutely does, aside from the fact that Insulin is a growth factor, which is very beneficial after a hard workout.
Just as how fat in the presence of high sugar/carb meals actually does the bad that we were taught fat does, we know without the sugar eating fat absolutely doesn’t make us fat or clog our arteries, the context matters!
It’s much more about how long Insulin is high, and when. Same goes for blood glucose, there’s a time when it’s beneficial, there’s a time when it’s not.
On the artificial sweeteners, until you’ve identified that you actually have a problem with them, there’s really nothing wrong with them. Doesn’t mean you should be slamming diet sodas all day long, a some aren’t a problem either.
People like to have something to blame, and then they run with it. Only one I have issues with (but only in high amounts) is Erythritol, my issue was bloating, but a lot of the sugar alcohols do that. I lot of people villainize Xylitol , yet ignore that it’s natural occuring in a bunch of fruits and some veggies. Go buy what trial and error shows works with you.