There are two mutations that prevent lactose-intolerance from developing in adults: one occurred in the ancestors of today’s northern Europeans, and the other occurred among the ancestors of the Masai. I wonder whether the mutations were what made milk-eating possible for these populations, or if they tried eating that way first and the mutations gave those who were trying an advantage.
What about all those healthy high carb low fat people?
I’ve always wondered exactly how these things happened! Not in general terms - we know, it’s some kind of new pressure or situation AND a mutation - but how it actually came about in those generations. Like – there was a drought and hunting was rough but somehow someone got ahold of some animal milk (fermented milk? fresh milk?) and a few adults tried it and everyone was horribly sick except for the one with the lactose mutation who… then got at least one woman pregnant? so that when that happened the next time around, there were MORE folks with that mutation?
While this does not address the milk issue specifically, you may want to look at this podcast. I have no idea how much scientific validity there is but it was really interesting. Bottom line, genes are not static but adapt to situations. Survival of the fittest maybe should have been survival of the those best able to adapt
@Saphire - I’m eager to read this. Epigenetic signaling is so interesting (from the little I’ve understood of it so far…)
Thank you!
The reason some people are naturally thin is due to genetics. In my family, the men on my mother’s side are that way. It is probably due to the fact that they do not readily develop leptin resistance when following a Carb based pattern. Weight gain (but not obesity) doesn’t develop until older, such as their late thirties or so. Diabetes doesn’t develop until even later, in their forties. However, other nutritional, detrimental conditions develop earlier. Here’s what they experience. Gout, Crohn’s, Tourette’s, Celiac’s, and Diabetes. They also seem to be very prone to Athero. To me, there appears to be a strong correlation between the trait of not developing leptin resistance with the appearance of these detrimental conditions. To me, it shows a pretty good example of Evolutionary Discordance.
My cousin, who was overweight but not yet obese, decided to follow my nutritional guidance. I put him on the typical 60/35/5% lipolytic macro, along Paleo guidelines. He dropped fat fairly easily, losing 60 lbs. over 60 weeks. It was not a linear loss, after eight weeks I had him start doing limited glycogen recompensation whenever he experienced a 10 day or more stall. That was the hardest part, as the more fat he lost, the happier he became, and the more strict he wanted to become. I had to constantly explain that he was going through an adaptive process, and eating a few more carbs for metabolic purposes was necessary. He’s now less than 20 lbs. from his naturally lean state that he was in High School.
Now, this is different for people like me, who readily develop leptin resistance. The adaptation process takes much longer, and in order to continue to lose fat being stricter is necessary, especially once eliminating/reducing lipogenic resistance issues, as well as making sure to follow a clear caloric deficit except during periodic recompensation.
16 years of research and practice. I have a limited background in Anthropology. It was very easy for me to understand the Paleo concept. My real emphasis over the last decade has been to develop the ability to explain it to people in an effective way, so they decide to try it.