Pretty sure all statins can lower HDL. Ill find a chart that compares them.
We already covered niacin / fibrates
A super low dose of statin and a low to moderate dose of fibrate might work to change betsy’s biomarkers.
But I’m sure I wouldn’t bother if it was my lab work. I’d try tweaking my eating in a major way and seeing what the effect is. But more likely I wouldn’t bother with lab testing I’d go for a walk and not even think of the lab. YMMV.
Hmm. I see more sources that say statins increase HDL, abeit negligibly.
Small confession here … I am not too interested in HDL or often LDL for that matter. Lowering LDL in secondary prevention seems useful to me but other scenarios I dont worry about in almost all scenarios. For primary prevention, the high NNT (say 100) to impact any meaningful change (like death from MI, or just MI) takes it off my priority list. I prioritize quitting smoking (NNT = 2) and exercising. A huge problem I see on a regular basis is people on statins with low HDLs. Maybe their HDLs are low not because of the statin but more because the muscle ache from the statins prevents them from walking and the stress from not exercising makes them smoke. (haha)
Low HDL in people taking statins is a real problem. I’m a bit surprised trial data showing increases in HDL. That being said, the goal of statins is LDL reduction and they dont have meaningful impact up or down on HDL really. And taking statins to change HDL seems like a bad idea.
