Its unclear, unfortunately. I’ve changed drugs multiple times,for instance (have a left-bundle branch block, which causes lowered ejection fraction, and one cardiologist was all-in on drugs; the other – younger one – took me off the high-powered drug, but put me on Jardiance, which is also for diabetics, but does well with people like me with arrhythmia). Those could cause changes.
And I was taking NMRs, and I would always get high "insulin resistance’ based on that, due to HDL parts being pegged high. While my HDL values were getting lower, my “insulin resistance” oddly got better.
This was Oct 2023, where you can see my HDL are pegged to the right (and were like that for a long time even HDLs into the mid 50s), HDL of 46:
This was Oct 2024, HDL still 46, but the two HDLs are no longer pegged to the right:
I’m assuming that drugs are causing this, because my diet hasn’t really changed much. Maybe a few more carbs in chocolate and yogurt, but it’s odd that that’s making my “insulin resistance” go DOWN.