Okay All, I wanted to share this. I got some Stomach Virus on Wednesday Night.
Muscle soreness, eventually explosive diarrhea. Along the way, I dosed up on Vitamin C.
And watched my CGM shoot up about 3.3 mmol/L (or from 4.7 to 8.0). That was 6G of C.
In capsule form. Each Gram of C is 1 G of carbs if you are interested. But 6G of crabs MIGHT take me out of ketosis… It never jacks my glucose up that high.
Now, the CGM MFG admits this is a known Problem. Since the CGM measures Interstitial Subcutaneous Fluid (and because I believe our bodies store things there to use them later), as the amount in the blood is pretty tightly controlled until you do an IV of Vitamin C…
Anyways, I went from 85 to 145 on regular measurements. or a 60pt swing.
60/18 = 3.3 mmol/L (European number, and A1C style)
Okay, the experiment today (I am 90% recovered. Still a bit explosive).
So, excess Vitamin C won’t change anything, LOL… (It is a natural laxative at extreme doses orally)… I am going to take 10G of Vitamin C, and check my CGM every 15 minutes.
I am going to compare this to my Keto-Mojo Glucose Readings at the same time. Keto does not typically recognize Vitamin C as Glucose, but the CGM (Libre) does.
I will use the difference in the numbers between the baseline of both, and changes of both, to calculate the increased amount of Vitamin C in mmol/L of my interstitual Fluid.
the reading Spiked about just past the 60 minute mark, but since I was not being scientific it could be as long as 75 minutes.
I will respond to this with 2 sets of numbers.
- What happens with the Initial Dose (FWIW 30 minutes after my max reading, I was still in the 130 range on the CGM but much lower in reality)…
- I will then do a SECOND DOSE of 10G of C orally. At this point, I am looking to see if I get a similar bump, or if it is constrained by something. I assume it will probably not rise to the 190 levels levels, but be capped.
I will report this back to the group. I am a huge fan of Vitamin C, it has served me well.
The goal here is to see if the CGM can be used as a hack for Vitamin C status. Especially in cases where you want to drastically increase Vitamin C levels.
The 3rd piece I will study is the impact on of IV Vitamin C on the CGM. Getting Vitamin C via IV allows up to 200 times the Blood Plasma Concentration of Vitamin C. But does THAT vitamin C leak into the Interstitial fluid? And will it be constrained. (I imagine here, that the level of saturation of the Interstitial will be the same as the Oral, but I have no idea. This would require a theory as to how your body removes a HUGE EXCESS of Vitamin C from Serum).
As a GOUT sufferer… I am ACUTELY aware that I may be risking a GOUT Attack. Gout feels like a Broken Toe Socket for me. SEVERLY painful. But I know how to treat it.
A Gout attack early on, may prevent the second or third stage of testing. (Vitamin C, like Uric Acid and Ketones all appear to compete for emptying… But I could be wrong).
This is what is great about being LIVING Science Experiments. (Well, when WE CHOOSE the experimentation freely, LOL)
In summary: Imagine being able to use a CGM type device while dealing with a chronic illness that responds well to Vitamin C… To accurately DOSE the Vitamin C to keep you as saturated as possible. And more so, to be able to understand the corresponding value of IV Vitamin C based on it’s ability to drastically increase the Serum levels, and potentially keep them elevated without bleeding into the ISF (Interstitial Fluid)… WOW