When our fat cells start to get full, they secrete a hormone, called leptin, that signals the hypothalamus in our brain that we don’t need to eat for a while, because we have enough energy in storage. When a high carbohydrate intake has elevated our insulin level, however, the insulin blocks the leptin receptors in the hypothalamus, and we can no longer experience satiety. Fortunately, lowering insulin helps the hypothalamus to regain its sensitivity to leptin, and our satiety signaling starts working again.
For me, this happened in the middle of a meal during my third or fourth week of eating keto. I was halfway through lunch, when suddenly I stopped being interested in food. For someone on the “see-food” diet, this was very weird. I mean, I still had food on my plate! Nevertheless I had to put it in the fridge for later, because I certainly wasn’t going to be eating any more for a while.
My satiety signaling has only gotten stronger in the year and a half since then.