@Daisy have you seen this today, pretty good at exposing diets that are too quick, not for long term etc.
Worth telling anyone who want to try weight watchers and waste their cash to watch this.
And now gone onto the myth about the Biggest loser, but unfortunately they have to bring in Kevin Hall.
why scared ? so far not going to mention Keto and stay on Keto you won’t put it back on, go back to carbs, I am afraid you will.
so far 35mins in and one mention of hormones Leptin and Gherlin nothing of insulin because that means carbs
Kevin Hall - no idea why some lose and some do not …
well he totally rejects Keto and Insulin theory and he totally embraces CICO, durrrr Kevin, don;t you get it ?
yes but he is presented as a leading expert … and the guy who can’t lose weight as blood sugar of 14 … makes me angry because sort the insulin out and weight comes off every time for the majority (and have to say especially men !!)
unfortunately he seems to have established himself as an expert yes but we know just how often experts are wrong so…
they should have got someone sensible like Mosely, Chatterjee or the other Brit GP who is great - dammit whats his name?
Why the hell go to the US for this and not even bring in success stories ??? Plenty of them in our world
I fucking hate Slimming World, and Weight Watchers come to that. My biggest diet regain was after WW.
I got really annoyed with the doctor who was talking about the alleged 5-10% of dieters who keep the weight off do two things.
Exercise at least an hour a day, every day
Make maintaining the weight loss the single most important part of your life.
Er… no. I can see how strength work exercise will have some impact. I can see how heavy duty cardio would impact to start with but not long term. And making it the most important thing… well no. I would argue the opposite, or at least lower in the ranks. Weight should not be your primary focus IMO, whether you are losing it, gaining it or maintaining it.
Daniel - I had hopes for him when he started talking and saying he learnt the science. But when he ends by saying this after talking about eating a bag of Haribo…
“I can justify it now because I know what I am doing”
No you don’t!
And now we are moving on to WW so I will probably lose my shit!
You know what? I am actually crying with frustration. I want the contact details fro every single person who was on this show.
Why does “having to live your life” = eating cake? FFS
I didn’t think that everything Kevin Hall said was BS - he actually said some sensible things around moving your focus away from weight as only goal.
I do sometimes feel like we know this incredible secret!
I agree he has the right idea on mental attitude and done General stuff. However she is an insulin theory denier because he believes carbs are needed. whilst he has this dogma he will not move on !
Again the programme agreed with a lot of us in that large calorific cuts never works as you are always hungry Etc but they never go into the next step !
I think that’s a pretty common attitude, especially among people who know a bit about how the body works. They know that the brain needs needs glucose (although most seem unaware that can also use ketones, even if it still needs some glucose), so they make the unjustified leap that therefore it requires carbs to be part of dietary input.
I was having a polite and friendly discussion with someone who had been a university teacher of biochemistry about gluconeogenesis, and I was saying that the body can not only make glucose out of protein, it can also make it out of the glycerol that partly results when triglycerides are metabolised. She disagreed, but I’m 99% sure I am right, and I think Steven Rose’s “The Science of Life” supports this*. (Although that book is disappointing when it comes to cholesterol and lipoproteins … in fact it doesn’t even mention lipoproteins (I have the 4th (revised) edition, 1999.
Anyway, she was convinced that the body needed carbs.
Glycerol is shown as one of the precursors of glucose in gluconeogenesis, along with lactate and amino acids. These first have to be converted into pyruvate. One interesting thing:
Gluconeogenesis Is Not a Reversal of Glycolysis
In glycolysis, glucose is converted into pyruvate; in gluconeogenesis, pyruvate is converted into glucose. However, gluconeogenesis is not a reversal of glycolysis. Several reactions must differ because the equilibrium of glycolysis lies far on the side of pyruvate formation. […]
great post @Mike_W_Ellwood and interesting I mentioned before I was talking to someone I know is a cardiologist and he basically old school nutrition.
think about what he does as a job and yet like with many as so little knowledge of nutrition I could cry. He deals with the end product and was arguing to me that carbs do not convert into sugar/glucose. I had to show him the diagram with the metabolism of it.
Amazing what a gap is missing though … a gap that could save billions if resolved by science and not based on a study of 40 years old !
Thanks @ianrobo. To be fair to my conversation partner, she is retired, and admitted she was a bit rusty in some details. I had already ordered (but not received) “The Chemistry of Life” (oops, got the title wrong in my last post) when I was having that conversation. It is very good in many ways (as far as I’ve got with it), but it’s obviously a bit behind with the latest developments.
The book in that link I gave (Biochemistry, 5th edition - Jeremy M Berg, John L Tymoczko, and Lubert Stryer.) looks a lot more complete (I looked at the preview on Amazon) and there are later editions. I’m tempted to buy it…but it’s over 1000 pages!
Interestingly, that linked excerpt from the book says:
Glycerol is a precursor of glucose, but animals cannot convert fatty acids into glucose, for reasons that will be discussed later (Section 22.3.7).
(I’m assuming that “animals” here includes the human animal). Perhaps that’s what my friend was thinking about if she thought "you cannot make glucose from “fat” (meaning fatty acids). However, if you interpret “fat” as the storage form, i.e. triglycerides, then you can make it out of one component of the fat, i.e. the glycerol.
What I’m not clear about now is whether glucose can be synthesised from glycerol alone, or whether it’s only in combination with either protein or lactate, or both.
(If there are any biochemists or others here who know for sure, do please shout out).
…oh wait (one google search later): Chris Masterjohn to the rescue!
https://chrismasterjohnphd.com/2012/01/07/we-really-can-make-glucose-from-fatty/
It’s not the question I asked exactly, but it’s even more exciting…the textbooks are wrong!
You can (apparently) convert fatty acids to glucose (although it may possibly be done only rarely).
I would still be interested in knowing if glycerol alone can be used to synthesise glucose.