Semaglutide, et al, to go "off off-brand"

(Joey) #1

For those interested in this topic…

(Bob M) #2

I did see that, which is too bad. It does help some people, and it’s so expensive normally. Off-brands help reduce the cost.

(You've tried everything else; why not try bacon?) #3

But cut into pharmaceutical company profits. How can the CEO keep his head up among all the other multi-billionaire CEO’s, if he can’t afford that tenth vacation house? :rofl:

(Bob M) #4

It’s definitely cash. I believe this was some type of patent issue, where they were allowed to make “generics”, but then there was a court review that reversed this.

I’ve heard a lot of people say that these drugs reduce their cravings or constant thinking about food. That alone seems useful.

I prefer not taking any drugs if possible, but if there’s something that reduces cravings for those people who have these, maybe that’s not a bad thing? (Assuming the incidence and severity of side effects is low, that is.)

(Joey) #5

I imagine we’re soon going to discover whether there’s a replacement craving for semaglutide. :thinking:

#6

There is, the Semaglutide you don’t buy at the pharmacy, and where the overwhelming majority of people in the biohacking and peptide worlds have been buying it the entire time long before it was a fad.

That stuff is going nowhere!

(Mark Rhodes) #7

Well he, and let’s be honest its mostly men, he can build an off brand and get even richer?

#8

That’s the thing, the FDA has no grounds to make that call. Much of this is from people wrongly calling it a “drug”, it’s not. It’s a peptide. On top of that, it’s a peptide that our body naturally makes. This same thing happened with HCG, they got called out on it, lost, and then all of a sudden HCG got reclassified as a biologic, which gave them more control.

The next step would be trying the hormone route, since it is. But so is DHEA, Melatonin and Insulin, which can all be bought over the counter without your doc and a money making scheme to bankrupt you on it.

In the end, those who were always on it, and those who even attempt to do any research will find very quickly that $1000 of 5mg of Peptide can be purchased for $50-$75 and they’ll go that way.

Most of the weight loss clinics which is the largest source of it outside of diabetics have moved to a per shot model and selling pre-loaded syringes to keep it a constant, but smaller financial hit.

Like always, gov’t morons have just sent an already gray market into nuclear overdrive.

(Joey) #9

This is where government policy lands between public health vs private rights.

The “libertarian” streak in me would love to see citizens having the freedom to decide what to put in their bodies. While the concerned citizen in me wants to protect people from dangerous products about which they tend to be ill-informed. (Dangerous can include improper dosing of an otherwise useful chemical.)

If we were all up the learning curve and could trust the producers of products, I’d think that letting the floodgates open would be appropriate for all drugs - including all meds currently requiring an Rx, “illicit” drugs, etc.

Given how ignorant vast segments of the population are about so many health issues - and how untrustworthy manufacturers can be without proper testing and oversight - there seems to be a place for an FDA to stand guard.

I guess I struggle with the proper balance… Just where such lines ought to be drawn can remain the subject of reasonable disagreement.