Peter Attia - Dr Jason Fung

(Eric - The patient needs to be patient!) #1

#59 – Jason Fung, M.D.: Fasting as a potent antidote to obesity, insulin resistance, type 2 diabetes, and the many symptoms of metabolic illness

I have not had a chance to listen to this. I hope he is not a jerk to Dr Fung. https://peterattiamd.com/jasonfung/

I may start to listen on the way home.

(Carl Keller) #2

LOL, I’ve heard more than one person say they are not a fan of Peter Attia. I’ve noted his personality is definitely alpha in the few lectures of his that I have watched. I’ve not really made up my mind about how I feel about him.

We discuss:

  • Comparing scientific disciplines: Medicine and biology versus physics [7:25];
  • The limitations of evidence-based medicine [12:30];
  • Early signs of metabolic disease: How specializing kidney disease gives Jason a unique insight into early indications of illness [20:50]
  • Insulin resistance, hyperinsulinemia, and the overflow paradigm [29:30];
  • Why the common treatments for type 2 diabetes seem to make things worse [42:30];
  • How hyperinsulinemia (not insulin resistance) drives metabolic syndrome [53:15];
  • Insulin and weight gain, and using fasting to empty the cells of glucose [59:30];
  • The two step process of developing type 2 diabetes and how they are both manifestations of hyperinsulinemia [1:03:15];
  • NAFLD and hyperinsulinemia: A vicious cycle [1:08:30];
  • Are the features and symptoms of diabetes actually protective? [1:12:15];
  • Is obesity causing insulin resistance or is it the other way around? [1:17:30];
  • What role does inflammation play in obesity? [1:21:45];
  • CVD and cancer: Diseases of too much growth? [1:27:30];
  • How to reduce proliferation with rapamycin, nutrition, exercise, fasting, and manipulating hormones [1:32:45];
  • Getting patients to fast: How Jason and Peter utilize fasting in their practice, and how their approach differs [1:40:15];
  • Comparing bariatric surgery to fasting as a treatment for type 2 diabetes [1:48:00];
  • Why people think that fasting is bad for you [1:55:15];
  • Time-restricted feeding and intermittent fasting: Defining terms, and how Jason applies them in his practice [1:58:30];
  • A fasting case study: A diabetic patient with a non-healing foot ulcer [2:04:00];
  • Keys to a successful fast [2:12:45];
  • Muscle loss during fasting, and why Jason isn’t worried [2:24:45];
  • Will fasting help a healthy person live longer? [2:31:30];
  • Does fasting cause gallstones? [2:38:45]; and
  • More.
(Eric - The patient needs to be patient!) #3

Yes. I don’t listen often because the podcasts are too damn long. I do learn a lot. But he sometimes lets his opinions get ahead of the science.

I’ll listen up some today. It will take most of the week to finish.

(Bob M) #4

I gave up on Attia years ago, when I realized the cognitive dissonance was strong in that one.

(Karim Wassef) #5

Awww… Peter’s cool. Just a teeny bit opinionated and strong willed.

#6

Sweet Valhalla, is it really almost three hours long? Gonna need to build up some fortitude to get through that one…

(Eric - The patient needs to be patient!) #7

I’m about 25 minutes in and so far so good. I hope to get some listening in before bed and then in the gym tomorrow. Dr Fung has a useful paradigm for what we can insulin resistance. I’m curious where this part of the conversation goes.

(Karim Wassef) #8

I just turn the speed to 2x

(Andi loves space, bacon and fasting. ) #9

This conversation is fascinating to listen to.

(Eric - The patient needs to be patient!) #10

Okay for me this was well worth the time to listen even at 1x speed.

  • Dr Attia was very respectful of Dr. Fung
  • Dr Fung’s model of hyperinsulinemia versus insulin resistance makes a lot of sense and seems to model my healing (but we are pattern matchers aren’t we)
  • Good info on fasting but not a lot of insight because, if you fast, you know that mechanically it is easy. Don’t eat. May not be easy on all fronts, I get that.
  • However the risk reward for fasting seems low. So even if you are healthy, why not try fasting just to see if there are benefits. There are virtually no risks to fasting in this regard.

They covered a lot of nuanced edge cases and more. I find that interesting but Dr. Attia’s podcasts go long because of his desire to go to the edge cases. That is one of the reasons I selectively listen to his podcasts.

I may listen to the front end again for the model of hyperinsulinemia versus insulin resistance.

(Polly) #11

Thanks for flagging this one up @daddyoh and for all the feedback on the podcast. I will try to listen later whilst ironing.

(Andi loves space, bacon and fasting. ) #12

Around the 2 hour mark, Fung talks about how low carb diets work great from some people, but some just don’t respond to them. I wonder if he is talking to me? I lost weight consistently from January - March when I was doing a 48 or more hour fast per week. Since March I haven’t fasted more than 24 hours and while I’ve been eating less than 20 net carbs per day, the scale hasn’t budged. I feel great and have been getting all of the other benefits of keto, but now I think that I just must fast in order to lose weight.

Good Lord I hope you don’t have 3 hours of ironing to do! :scream:

(Polly) #13

The pile had got a little high, but I am almost through it now.

About half way into the podcast and it has definitely been worth a listen so far.

(Eric - The patient needs to be patient!) #14

I seem not to loss wt unless I fast. So I fast. But I am also working out and building some lean muscle mass, slowly anyway.

(Erin Macfarland ) #15

Blockbuster episode

#16

I’ve listened to a lot of Dr. Fung’s guest spots on other podcasts, and he has a certain basic script that he tends to cycle through. (Which I totally get. He has a message to communicate, and the audience is mostly lay people.) I was hoping to hear a more in-depth, scientific look at his work, and he did not fail to deliver. I’m so happy I gave Attia another chance and that he provided Dr. Fung with a forum for presenting this information in a long-form, conversational way. I love that they have so much time and it really flew by for me.

(Carl Keller) #17

You can say that again. This clinches it for me.: