I think this is an important topic raised in another thread where safi commented that maybe the large lean mass loss in my legs (during my 19 day fast) may not have been muscle.
I had never considered that this could be actual empty fat cells (the protein sac) being cannibalized once the lipids have been removed.
Three data points:
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My squat strength has recovered on refeeding even though my leg mass (size) has not.
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My wife commented that my thighs are leaner and more vascular.
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I historically stored my fat in my belly/waist and inner thighs. The inner thigh fat was already substantially reduced visually even before the fast.
Thoughts on this? Is it likely that my lost leg mass is empty protein adiposite sacs?