I understand the antibiotics part, but why PPI?
fact 1:
H.pylori likes low gastric acid
fact 2
PPI reduce gastric acid secretion
I understand the antibiotics part, but why PPI?
fact 1:
H.pylori likes low gastric acid
fact 2
PPI reduce gastric acid secretion
Omar. Hello old friend. Itâs been a while.
I donât know about it âlikingâ low acid, but it does act differently over the pH range. âLow pHâ is one thing, while âlow acidâ is the opposite - higher pH.
In a more acid environment, H. pylori is resistant to antibiotics. So, to make the antibiotics effective, the pH needs to be raised, made less acidic.
Our stomachs are usually at a pH of 1.5 to 3.5, very acidic. Below a pH of 6, H. pylori is in its âcoccoid formâ where it doesnât replicate or multiply, does not âgrow,â but it can survive in very harsh conditions in that form.
Above a pH of 6 is where it replicates, but thatâs also where antibiotics can kill it. So, stopping the stomach from secreting as much acid is part of the treatment - necessary for antibiotics to work.
The doctor performed upper endoscopy
The nurse said no H.Pylori, and gave me 2 prescription, a PPI and calcium blocker
But there are findings
1-Esophagus
Linear erythema of the lower segment, partiality incompetent cardia, and reflux of the gastric
2-Stomach
Diffuse erythema involving the whole gastric mucosa especially, the antrum. On retroversion, Stigmata of sliding hiatus hernia about 1 cm width X 2cm length
3-Pylorus
Round, regular and reactive
4-Duodenum
Marked Bulbitis
I did not see the doctor yet. But the nurse said no H.Pylori.
Not sure I understand the report, because I dont have GERD. But I have pain in the esophagus. Kind of lack of comfort rather than pain.
scary words
Diffuse, incompetent cardia, Stigmata of sliding hiatus hernia
I will ask him next appointment