Food sensitivity breath tests for fructose, sucrose while on keto

(betsy.rome) #1

I’m taking a series of food sensitivity breath tests with my gastroenterologist. So far I’ve tested positive for SIBO (lactulose test), and have taken the recommended antibiotics & probiotics after treatment. I’ve passed the lactose & celiac (gluten) tests.

Last week I did the test for breath test for fructose, and my numbers were high, just short of a positive result. The test involved drinking a solution of fructose dissolved in water (really sweet & disgusting) and testing breath every 30 minutes for 3 hours after.

My question is this: could being keto for over 2 years skew the test results? as I do not normally eat fructose except in small amounts in berries, onions or garlic. I do not expect my doctor to know about keto exceptions to the rules.

Later this month I’m due to take the sucrose breath test, so I am wondering that if the fructose test could be affected by keto, the sucrose could be also. Not looking forward to my upcoming sucrose cocktail!

(TJ Borden) #2

Yes!!! If I recal correctly (which is a crap shoot at best), you actually need to ditch keto for a couple weeks prior to a test like that.

(betsy.rome) #3

Where can I find the science to discuss this with my doctor?

(TJ Borden) #4

That I don’t know. This is very likely a scenario where you’ll have to accept you know more than the doctor and just collect whatever data you can

(betsy.rome) #5

I’m trying to recall where I heard or read about the GTT (glucose tolerance test) results being different if you’re keto. Didn’t @richard interview someone with a kiwi accent about the GCC and Dr. Kraft?

(TJ Borden) #6

:joy::joy::joy::joy: that’s what I’m remembering too, but that doesn’t narrow it down much

(Bunny) #7

Never thought about this from this aspect but found some interesting things related to it:

  1. Fructose Malabsorption and Intolerance: Effects of Fructose with and without Simultaneous Glucose Ingestion
  1. ALL ABOUT FRUCTOSE MALABSORPTION (a paleo-perspective)
  1. New Study to Determine the Role of Glucose & Fructose in Disease: (very long you will have to scroll down to it, to get to the excerpted dialogue I am citing)

Dialog:

RICK: Collaboration would be wonderful. And the other possibility is that the low carb diets improve insulin resistance in part because of reduction of dietary glucose that reduces endogenous fructose. When you become insulin resistant, your aldose reductase goes up and so you start making endogenous fructose. We’re doing studies right now with fructokinase knockout animals to specifically check that pathway.

STEVE (Phinney): I hadn’t considered endogenous fructose production.

RICK: It’s very important.

STEVE (Phinney): The pathways for disposal of dietary fructose are very different from the disposal in the fructose 6-phosphate pathway. They don’t cross. But endogenous fructose? Is there a place I can read about that. …More

  1. Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome
  1. Endogenous Fructose Production and Fructokinase Activation Mediate Renal Injury in Diabetic Nephropathy
  1. Targeting fructokinase, endogenous fructose production and purine degradation for the prevention and treatment of hereditary fructose intolerance
  1. A novel Role for endogenous fructose production and metabolism in the pathogenesis of contrast-induced nephropathy
  1. Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome
  1. Researchers link obesity and the body’s production of fructose
  1. High salt intake causes leptin resistance and obesity in mice by stimulating endogenous fructose production and metabolism.
(Richard Morris) #8

Dr Catherine Kroft