Episode 76 with Dr Richard Feinman

[Sheri_Knauer]

I just listened to this episode yesterday, which was very informative. I have one question though. @richard you were starting to ask him a question (at the 38:49 minute mark) regarding lactic acid and how it goes in and out of the cell through the same mechanism as ketones and when we become fat adapted… then Dr Feinman started to talk and you didn’t finish that question and I was curious what it was you were going to ask or where you were going with that. I have been keto a year and have been an avid exerciser for 25+ years (mainly lifting). More times than not, I would have DOMS either 1 or 2 days after working out. Since being fat adapted, I don’t get sore anymore. Not one bit and I was always curious why and I am wondering if it has anything to do with that mechanism or were you going someplace else with that comment. Ive heard people say its because of lower inflammation but that really never explained why.
Thanks!

[richard]

Yeah I am the same. I don’t get the 2 day DOMS anymore.

Less inflammation will have some effect, but the specific effect I was referring to is an up-regulation in the expression of the Monocarboxylate transports (MCT) that transport lactate, pyruvate and ketone bodies. In the process of becoming better at getting Ketones into our cells we also become necessarily better at shuttling lactate out of them. So, in theory, we become better at shuttling lactate out of our muscle cells and into circulation to be turned back into new glucose in our livers.