Eating the same poison ...Twice

(Mel Day) #1

Does anyone have any Science on this? Since cells membranes are built using the foods we consume I’ve read that this is why we have compromised cell structure after years of an inflammatory diet of crappy carbage and vegetable oils. This makes sense. BUT THEN!!!; My question is: when I fast and actually fuel my body with that ‘Krispy Crème donut I ate years ago’, am I not fueling my body with damaged protein and fat? Like eating the same poison twice??

(You've tried everything else; why not try bacon?) #2

Fat, yes, protein, no.

The body has no mechanism for storing protein, and damaged proteins are broken down into their constituent amino acids, which are then reassembled into other proteins. Every protein has a “lifespan,” which depending on the protein can be as little as a few minutes or as long as a few years. Because damaged proteins can wreak havoc on the body, there are mechanisms to break them down into their constituent amino acids as soon as possible. Proteins are vulnerable to damage, because they must be folded into the correct shape in order to work properly. Any protein not matching its genetic template gets dealt with pretty quickly. Except under rare circumstances, protein is never metabolised, because it takes quite a bit of energy to break it down, and not much ATP can be produced from it.

Fat from the diet gets circulated in the blood in lipoproteins called chylomicrons. Most of it gets metabolized, although some can get used in the walls of cells (cell membranes are mostly fatty acids and cholesterol). The fat from your adipose tissue gets packaged into VLDL by the liver and sent around to the muscles to be metabolize. As the VLDL is transformed into LDL, it gets scavenged and returned to the liver. I am not sure how much, if any, of the fat contained in VLDL gets use to build cell membranes. @richard might know. I’m sure if I got anything mixed up in the foregoing, he can set us all straight.

(MooBoom) #3

This is a super super interesting question Mel! Thank you for asking it. I am following with interest.

(Little Miss Scare-All) #4

@PaulL always with a great answer. Thanks!

(Running from stupidity) #5

That’s not actually happening, is the simple answer - you’re fuelling your body with the STORED ENERGY from that donut.

(Richard Morris) #6

The VLDL has a phospholipid membrane, cells that are growing engulf the particle and use it’s phospholipids rather than manufacturing their own.

#7

I read something awhile back about this that hypothesized about all the junk that’s released as we use up old fat stores. It’s all the fat soluble stuff when it’s stored there, so when it starts circulating the body it needs to be flushed out…
The old “drink lots of water to flush out toxins” adage doesn’t help because these things are fat soluble. BUT when you are eating lots of fat, it provides a sort of escort for fat soluble undesireables to be excreted from the body safely. So for those on super low-fat weight loss diets, they are lacking these helper fats and have more trouble getting rid of it all. But keto is awesome and allows our bodies to cleanse themselves with fat. :smile:

This may or may not be true.

#8

I wonder how this relates to eating keto

#9

Dr James DiNicolantonio often brings up the issue of persistent organic pollutants in podcast interviews. I’ve read his book ‘The Salt Fix’ but haven’t read the one he co-authoured with Mercola on fats - I think it’s called ‘Superfuel’. There may be more info in that.

(Running from stupidity) #10

I wouldn’t, either. I get that Mercola has a huge audience and thus has a lot of appeal as a co-author from that POV, but he’s such a charlatan I wouldn’t go near it.

#11

Exactly :slightly_smiling_face:

(Omar) #12

Dr Mercula remind me of car dealers in Houston, tx.

I would rather walk and not buy a car from most of them.

(Mel Day) #13

TNorth…That article is pretty spot on for this discussion!

edited & cherry-pickedby me with POP being Persistant Orgnic Polluants and AT being AdiposeTissue<<
“Fatty foods of animal origin (e.g., meat, fish, dairy) are important vectors of several classes of POPs, including dioxins and polychlorinated biphenyls (PCBs).
" POPs tend to distribute into lipophilic compartments, particularly the AT.”
“If increased blood levels of POPs during weight loss are related to their release from AT, changes in AT POP content would be expected”
“Evidence from wildlife indicates that fasting and AT loss increase circulating POPs.”
"A critical issue is whether the release of POPs from AT during weight loss could also lead to toxic outcomes in other organs and tissues of humans. (Evidence from Bariatric surgery presented) This suggests that POPs may counteract the positive effects of weight loss on hepatic and serum lipids"
Article concludes more information is needed.

This is a wrinkle I hadn’t considered when posing the original question, but it relates to mobilizing that bloody Krispy Kreme Donut. (I may have had more than one :face_with_hand_over_mouth:)
It might further explain random health events while fasting as hitting a toxic pocket of stored energy packets.