Anyone have Latent Autoimmune Diabetes in Adults (LADA)?


(libbyg2109) #1

I am developing this, which will make me insulin dependent. I have held it off eating keto for almost 3 years. It is not Type 2, but known as Type 1.5. I test daily but endo has me on no meds currently. I anticipate having to go on mealtime insulin soon, as my blood sugar is slowly rising. I know I have done everything in my power since diagnosis to hold it off (strict keto, lost 75 pounds), but I am so fearful of having to take insulin and gaining weight. Anybody where I am?


(O. Kur) #2

Why should you gain weight by taking insulin? See it the other way round: you will then have complete control of your insulin levels. I lost about 40 pounds after the diagnosis and am doing very fine (my A1c is below 5%), so no problem, only some minor circumstances because of the technical things. But you will get used to it in no time.


(libbyg2109) #3

Did you start with mealtime insulin? My 2 hour postprandial bs was 147 today, and that is becoming common on a strict ketogenic diet. A year ago I was in the 80’s.


#4

Hi Libby. :grinning:

I’m curious about this condition.

Can I ask you how you were diagnosed? Did you have positive antibody test results? Did you have low insulin levels? Were you insulin resistant or insulin sensitive when you started keto?

Thanks!


(libbyg2109) #5

Yes, diagnosed by an autoantibody test. I was borderline Type 2 as well, and insulin resistant. I was producing low normal insulin at the time. Just a big, fat mess. Referred to endocrinologist, who concurred. Told me no type 2 meds would help. Has me test daily and eat keto. Type 2 went completely away. In the last 6 months my blood sugar has climbed, but endo told me when I saw him last that I’m ok until it is 200, which freaks me out. He did suggest I might start mealtime insulin soon. I see him again mid November. I know there is nothing more I can do from a dietary perspective. I would have long ago been insulin dependent if I ate a standard diet. I’m feeling so anxious about this. I don’t want it to be this way. I have worked so hard and come so far by losing the weight and staying in the ā€œhoneymoon phaseā€, but it’s all crumbling now. I have lost no weight in months, and I don’t feel great like I did before. Ugh!!


#6

Thanks Libby. I’m really sorry to hear about your situation. I’ve been listening to a diabetes dr- Richard Bearnstein. I’m curious to know if you’ve heard of him or have an opinion about his advise. I’m confused about my situation bc i am currently insulin sensitive and thin. I seem to have low pancreatic function- which i think relates to my higher blood sugars. My antibody test panel was negative though. I have found Besrnstein very interesting- though right now I’m doubling down on my diet and exercise. Thanks again and good luck. :grinning:


(Bunny) #7

Some points of interest:

•Interestingly you produce little to no insulin (i.e. type 1 diabetes, type 1.5, LADA and MODY)

•The lower carb you go, the more you will use ketones as fuel rather than glucose/glycogen…


(libbyg2109) #8

Yes, I know I have done and am doing everything I know to do from a dietary perspective to keep this LADA at bay. The stress of seeing it slowly happening is so damaging, I am sure, but what do you do? I have a lot of faith and a doctor who assures me we will just ā€œtreat itā€ when it happens, but still it is like waiting forcthe guillotine to drop.


(libbyg2109) #9

I have his book, ā€œDiabetes Solutionā€. I tried to read it and it stressed me out, so now I just look at it on my coffee table. I guess you would say I am in denial. We are in a mess, aren’t we?


(Bunny) #10

I searched high and low and the only thing that has any inkling of promise for LADA is this pay-walled research paper (what I originally suspected {leaky gut} and maybe what is used to reverse this can also be used to reverse this (LADA)?)

I sure would like to read the entire paper (below) because what ever it reveals has some monetary value to the researchers…

Is there a role for gut microbiota in type 1 diabetes pathogenesis?

Abstract

Type 1 diabetes mellitus (T1D) is an autoimmune disease characterized by insufficient insulin production due to the destruction of insulin secreting β-cells in the Langerhans islets. A variety of factors, including chemicals, viruses, commensal bacteria and diet have been proposed to contribute to the risk of developing the disorder. In the last years, gut microbiota has been proposed as a MAIN FACTOR in T1D pathogenesis. Several alterations of gut microbiota composition were described both in animal model and in humans. The decrease of Firmicutes/Bacteroides ratio was the most frequent pattern described, in particular, in human studies. Furthermore, Bacteroides , Clostridium cluster XIVa , Lactobacillus , Bifidobacterium , and Prevotella relative abundances were different in healthy and affected subjects. Dysbiosis would seem to increase INTESTINAL PERMEABILITY and thus promote the development of a pro-inflammatory niche that stimulates β-cell autoimmunity in predisposed subjects. Preliminary studies on animal models were realized to investigate the role of gut microbiota modulation as therapy or prevention approach in predisposed animals: promising and stimulating results have been reported.

•Key message
• Dietary antigens and microbiota-derived products might act as triggers of T1D by causing a pro-inflammatory and metabolic dysfunctional environment.

See also:

  1. Army vet is ā€˜first in the world to CURE his type 1 diabetes – thanks to diet, exercise and mutated gene’ A/K/A: ā€œMiracle Danā€ ā€œā€¦The former British Army Grenadier Guard believes his diet, which is high in zinc, nuts, oily fish and veg, and a love of running more than 60 miles a week are the secret to his unbelievable reversal of the incurable autoimmune disease. ā€¦ā€

(libbyg2109) #11

I believe 100% i have had leaky gut for a long time. I have Hashimoto"s, which is also autoummune. The article about the guy who cured Type 1 is interesting and encourages me to take zinc, eat fatty fish and nuts (all allowed on keto). But running 60 miles a week won’t be happening to this grandma…lol!