That’s all fine, Bill, and I am sincerely sorry about your sister dealing with hypothyroidism. I know it’s probably well-managed and all, and she doesn’t require anyone’s sympathy, but chronic disease sucks and I hope she continues to be successful managing it.
No one is saying CICO isn’t part of the puzzle, we’re mostly saying it’s a relatively rather small part of the puzzle, while you appear to be saying it’s much bigger. That’s all. I honestly don’t see how your examples refute what I’ve said about the problem of oversimplifying cause-and-effect relationships, and maybe you didn’t intend them to. And I’m not one to argue for argument’s sake (most of the time ), so I’ll just wish you the best of luck!