Hence the “fringe” designation
Myocardial Infarction after 2 yrs of keto
I’d be curious to know where the vitamin K antagonists are coming from. Seems to me that’s the issue to address, not patching the problem by supplementing with vitamin K.
Could be. Hard to tell. I’d point my finger toward vegetables, only because I’m (somewhat) anti-vegetable. (Though I also ate natto for quite a while.)
Then again, I had a horrible diet for a long time, and still got a CAC score of zero. That was after 5.5 years keto, though.
This is why I think Malcolm Kendrick has the best ideas with respect to heart disease: whatever negatively influences the endothelium causes heart disease; whatever repairs or benefits the endothelium limits or protects against heart disease.
So, pollution can cause heart disease, as can stress, smoking, etc. Whatever I did (including likely having “good” genetics, and probably exercising) prevented/limited calcification.
In an area like this, I think there’s not enough info. Even the CAC scan is relatively new, or at least I’d never heard of it until a few years ago. So, it’s hard to know what affects it (other than it’s most likely NOT LDL).
By antagonists, are you suggesting there are factors suppressing the bioavailability of dietary Vit K2?
My understanding is that we are not getting nearly the amount of K2/M4 and K2/M7 we used to (i.e., evolved to) get. And that this was due to a confluence of factors like proliferation of indoor animal “factory” farming, reduction in grass-fed livestock, and our generally eating less, if any, of the animals’ vital organs (replaced almost entirely by our preference for muscle tissue).
If this is accurate, then wouldn’t it be our lacking sufficient levels of K2 in our diet rather than antagonist components getting in the way of our ability to process the K we do digest?
From the abstract of the study linked above:
Both preclinical and clinical studies have shown that inhibition of the vitamin K-cycle by vitamin K antagonists (VKA) results in elevated uncarboxylated MGP (ucMGP) and subsequently in extensive arterial calcification.
So my question is, where are these antagonists coming from? I know nothing about the rest of your post, so can’t comment on that, sorry.
can you get a consult with a keto friendly , boarded cardiologist? even remotely/telehealth? they may or may not want you to adjust your diet and /or add a statin or other meds - but they certainly will be more familiar with your keto influenced lab results.
IMHO GPs should not prescribe statins or psych meds. the science around them is changing all the time.
My recovery has been as strange as the initial experience. I’ve felt no adverse discomfort, shortness of breath, fatigue. My follow up appointment is later this week. I don’t have anything to tell the cardiologist. I do have many questions thanks to the many that have offered insights here. Thanks so much for inquiring. Thanks so much to all for sharing. I feel so fortunate to have found this learned community.
Owen Dougherty
OtisWood,llc