I think it’s Newton’s law of motion:
“An object at rest remains at rest, and an object in motion remains in motion at constant speed and in a straight line unless acted on by an unbalanced force.”
Once something gets started, it’s almost impossible to stop it.
Another issue seems to be the scientific mind. I think that if E=mC^2 fails once, it fails. It’s wrong. If I find a person with extremely high LDL and no atherosclerosis, that means to me that LDL does not cause atherosclerosis. But these people keep on the train, regardless of any evidence against it. I can’t understand why.