Alkaline Phosphatase

(Tracey Porreca) #21

Actually, it is a very useful test for bone metabolism, and for diagnosing hypophosphatasia, which is a much more common disorder than most physicians realize. Any adult who is being worked up for osteoporosis, for example, must have an ALP run as the drugs which improve osteoporosis (bisphosphonates) actually make HPP worse. It is very important to differentiate between true osteoporosis and undiagnosed HPP

(Tracey Porreca) #22

Please don’t ignore. Please see my other comments. It is important to know this level and why it is low or high.

(Tracey Porreca) #23

Please please see my comments on this thread regarding low alkaline phosphatase (ALP) levels. This could be an undiagnosed condition that is important to be aware of. Both of you should consider being evaluated for this as not many things can lead to low ALP levels. Please follow the links in my long post regarding this.

#24

My level pre Keto was 98

(Darlene Horsley) #25

Seen and noted. Thank you.

(Tracey Porreca) #26

Please see my other comments and look into the possibilities of hypophosphatasia (HPP). ALP is present in bone, and also in liver as mentioned. But there is a form of ALP called TNSALP or TNAP. This stands for tissue nonspecific alkaline phosphatase. It is present in virtually every system in the body, and deficiency in this enzyme is the hallmark of HPP. It is TNSALP and not bone or liver specific ALP that is part of a chemistry panel you would get at your doctor’s office. It is important to know the difference, and important to know what to do if you are deficient

#27

Hi Darlene. A low ALP result can indicate magnesium or zinc deficiency. There are recent scientific papers (2017) investigating the link between low ALP and those deficiencies. So I guess a mineral deficiency is a specific form of malnutrition, if the cause is nutritional; the food (or water) being deficient as compared to an inability to absorb a nutrient. It’s worth investigating as magnesium and zinc deficiency can lead to other, related, health problems. Thanks for starting this discussion thread.